2012年EASL慢性乙型肝炎病毒感染临床实践指南解读

万谟彬

2012年EASL慢性乙型肝炎病毒感染临床实践指南解读

万谟彬

第二军医大学长海医院感染科

基金项目:

国家自然科学基金资助项目(30972600)；

详细信息

中图分类号: R512.62
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- 文章访问数: 184
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- 被引次数: 0
出版历程
- 出版日期: 2012-06-20

Interpretation:EASL Clinical Practice Guidelines: Management of chronic hepatitis B virus infection (2012)

Wan MoBin

Research funding:

摘要

摘要: <正>最近,EASL官方网站上公布了新一版EASL慢性乙型肝炎临床实践指南（2012版）[1],这是在2008版[2]的基础上经增加新近文献,对部分内容进行的更新。更新版指南仍保留了前几版指南的一贯体例和鲜明特点。（1）在文献综述同时穿插其中逐条列出循证证据和提出临床处理推荐意见;（2）重要循证证据文献和推荐意见后逐一列出循证证据级别和推荐强度。循证证据级别和推荐强度分别按GRADE（Grading of Recom-mendations Assessment Developmentand Evaluation）系统确定。
- 肝炎,乙型,慢性 /
- 指南,临床实践 /
- 治疗,抗病毒
- hepatitis B /
- chronic /
- guidelines

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参考文献(13)

[1]European Association for the Study of the Liver.EASL ClinicalPractice Guidelines:Management of chronic hepatitis B virus infec-tion[J].J Hepatol, 2012, Mar20.[EPub ahead of print].

[2]European Association for the Study of the Liver.EASL clinical prac-tice guidelines.Management of chronic hepatitis B[J].Gastroen-terol Clin Biol, 2009, 33 (6-7) :539-554.

[3]Lok ASF, McMahon BJ.Chronic hepatitis B:update 2009[J].Hepatology, 2009, 50 (3) :661.

[4]Chang TT.APASL 2012 HBV Guideline[J].Hepatology Int, 2012, (in press) .

[5] 中华医学会肝病学分会, 中华医学会感染病学分会.慢性乙型肝炎防治指南 (2010年版) [J].临床肝胆病杂志, 2011, 1 (1) :Ⅰ-ⅩⅥ.

[6]Hou JL, Ma H, Sun J, et al.Baseline and early on-treatmentcharacteristics in patients with chronic hepatitis B (CHB) infectionachieving an early on-treatment response to Peg-interferon Alfa-2A:interim results from the RGT study[J].Hepatology, 2011, 54 (4) (Suppl) :1021A.

[7]Zoutendijk R, Reijnders JG, Brown A, et al.Entecavir treatmentfor chronic hepatitis B:adaptation is not needed for the majority ofnave patients with a partial virological response[J].Hepatology, 2011, 54 (2) :443-451.

[8]Zoulim F, Locarnini S.Management of treatment failure in chronichepatitis B[J].J Hepatol, 2012, 56 (Suppl1) :S112-S122.

[9]慢性乙型肝炎联合治疗专家委员会.慢性乙型肝炎联合治疗专家共识[J].中华实验和临床感染病杂志 (电子版) , 2012, 6 (1) :60-64.

[10] 万谟彬.联合治疗是战胜慢性乙型肝炎的必由之路[J].中华肝脏病杂志, 2012, 20 (2) :86-88.

[11]Xu WM, Cui YT, Wang L, et al.Lamivudine in late pregnancy toprevent perinatal transmission of hepatitis B virus infection:a multi-centre, randomized, double-blind, placebo-controlled study[J].J Viral Hepat, 2009, 16 (2) :94-103.

[12]Han GR, Cao MK, Zhao W, et al.A prospective and open-labelstudy for the efficacy and safety of telbivudine in pregnancyfor theprevention of perinatal transmission of hepatitis B virus infection[J].J Hepatol, 2011, 55 (6) :1215-1221.

[13]Han L, Zhang HW, Xie JX, et al.A meta-analysis of lamivudinefor interruption of mother-to-child transmission of hepatitis B vi-rus[J].World J Gastroenterol, 2011, 17 (38) :4321-4333.

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