原发性胆汁性肝硬化的发病机制及影响预后的危险因素研究进展

刘红虹; 福军亮; 付宝云; 张政; 徐若男; 罗生强; 施明; 李永纲; 王福生

原发性胆汁性肝硬化的发病机制及影响预后的危险因素研究进展

1. 军医进修学院
2. 解放军第302医院中西医结合肝病诊疗与研究中心

基金项目:

国家“艾滋病和病毒性肝炎等重大传染病防治”科技重大专项项目(2009ZX10004-309)；

详细信息

中图分类号: R575.2
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出版历程
- 出版日期: 2012-02-20

The pathogenesis and risk factors related to prognosis of primary biliary cirrhosis

Research funding:

摘要

摘要: 原发性胆汁性肝硬化(PBC)是一种原因不明的,自身免疫介导的,以肝内中、小胆管胆汁淤积为特征的肝病。本文就目前国内外已报道的PBC的发病机制及影响其预后的相关危险因素进行综述。
- 肝硬化,胆汁性 /
- 发病机制 /
- 预后 /
- 危险因素
Abstract: Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease characterized by autoimmune-mediated destruction of small-and medium-sized intrahepatic bile ducts.Although many studies reported that PBC results from a combination of multiple genetic factors and superimposed environmental trigger, the precise mechanisms under the disease progression are still unknown.We summarized the pathogenesis and risk factors related to prognosis of PBC in this review.
- live cirrhosis /
- biliary /
- pathogenesis /
- prognosis

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参考文献(26)

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