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结缔组织生长因子在雌激素信号通路参与肝纤维化发生中的作用

韩聚强 徐小洁 叶棋浓

引用本文:
Citation:

结缔组织生长因子在雌激素信号通路参与肝纤维化发生中的作用

基金项目: 

国家自然科学基金资助项目(30972594); 王宝恩肝纤维化研究基金资助项目(20100025); 

详细信息
  • 中图分类号: R575.2

Connective tissue growth factor regulates the pathogenesis of hepatic fibrosis through estrogen receptors (ER) signal transduction

Research funding: 

 

  • 摘要: 临床流行病学资料显示肝纤维的发生存在有显著性别差异。研究证实,雌激素通过雌激素受体信号通路直接参与调控肝纤维化的发生。结缔组织生长因子是一种重要的肝纤维化发生相关细胞生长因子,其可能作为雌激素受体共调节因子,直接调控肝纤维化的发生。

     

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  • 出版日期:  2012-01-20
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