Abstract: Objective To evaluate the clinical security and feasibility of the transumbilical single-incision laparoscopic surgery in hepatobiliary diseases.Methods 71 cases of transumbilical single-incision laparoscopic surgery performed between May 2010 and May 2011 in the department of general surgery affiliated to Siping center hospital were analyzed.39 patients were diagnosed with cholecystolithiasis, 15 patients were diagnosed gallbladder polypus, 14 patients were diagnosed with hepatic cyst, and 1 with hepatocellular carcinoma.Results The transumbilical single port laparoscopic cholecystectomy of 69 cases were completed successfully while 2 cases were converted to routine laparoscopic cholecystectomy due to difficulties in operation.69 successful cases include 54 cases of laparoscopic cholecystectomy, 14 cases of laparoscopic fenestration in hepatic cyst, and 1 case of laparoscopic partial hepatectomy.There were no postoperative complications such as jaundice, bile leakage, bleeding, wound infection occurred.All cases showed a small or invisible scar.Conclusion Now the transumbilical single-incision laparoscopic surgery is a difficult procedure, Patients should be selected carefully to complete the procedure, The technique results in superior cosmesis.