Abstract: Objective To explore the clinical features of myocardialase spectrum, electrocardiogram and echocardiography in viral hepatitis patients complicated with myocardial injury.Methods Clinical data including myocardialase spectrum, electrocardiogram and echocardiography in 158 cases of viral hepatitis patients was collected and analyzed.Results An incidence of abnormal myocardialase spectrum in patients with hepatitis A was higher than in patients with hepatitis B, hepatitis C and hepatitis E (P<0.05) .Main abnormal myocardialase spectrum was decreasing of myoglobin and increasing of lactic dehydrogenase.There was difference between patients with hepatitis A and hepatitis C, between patients with hepatitis B and hepatitis C (P<0.05) .The difference in decreasing of myoglobin was observed between acute hepatitis and chronic hepatitis (P>0.05) , but not existed from increasing of lactic dehydrogenase (P<0.05) .There was difference in myocardialase spectrum between chronic mild hepatitis and sever hepatitis.Abnormal myocardialase spectrum was not associated with replication status of hepatitis B virus and hepatitis C virus.Abnormal electrocardiogram was observed in 77 cases with an incidence of 66.37% and abnormal echocardiography was observed in 14 cases (14.43%) .The symptoms of palpitation and chest distress only existed in 2.58% of viral hepatitis patients.Conclusion There was decreasing of myoglobin and increasing of lactic dehydrogenase in viral hepatitis patients.The abnormal myocardialase spectrum was associated with kinds of virus and inflammation of liver, but was not associated with replication status of hepatitis virus.There was abnormal electrocardiogram and echocardiography in viral hepatitis patients.The abnormal electrocardiogram and echocardiography was neither associated with kinds of hepatitis nor replication status of hepatitis virus.Myocardial injury of viral hepatitis patients mainly was subclinical.