The discussion on the issues related to NCCN clinical practice guidelines in oncology for pancreatic adenocarcinoma (V2011)
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摘要: 《NCCN胰腺癌临床实践指南》2011中国版已修订完成,新版指南在原有内容基础上结合近年来临床研究进展,在胰腺癌的诊断和治疗路线、原则、循证医学证据上进行了细微更新,并在理念上有了新的阐述,本文就更新中的相关问题进行探讨。《NCCN胰腺癌临床实践指南》2011版中针对胰腺癌的诊断提出了多学科评估的理念,治疗上重视肿瘤可切除性判定标准,化疗中对于体力状态好的患者可选用FOLFIRINOX方案,强调了吉西他滨和5-氟尿嘧啶(5-FU)均作为胰腺癌化疗的I类证据。Abstract: The revision of the Chinese version of NCCN clinical practice guidelines in oncology for pancreatic adenocarcinoma (V2011) has been completed.Based on the clinical research in recent years, the new version of the guidelines expressed new ideas and made minor updates on the diagnosis, treatment, and evidence based medicine of pancreatic adenocarcinoma.This article discusses issues related to these new updates.NCCN pancreatic adenocarcinoma guidelines (V2011) presented the concept of multidisciplinary review and emphasized the criteria defining resectability status in treatment.In addition, greater emphasis was placed on the principles of chemotherapy.FOLFIRINOX therapy was recommended for patients in good physical condition.Gemcitabine and 5-FU were also highlighted as Category 1 evidence for chemotherapy of pancreatic adenocarcinoma.
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Key words:
- pancreatic neoplasms /
- practice guideline
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