血管内皮生长因子与非酒精性脂肪性肝病

李娟; 张岭漪

血管内皮生长因子与非酒精性脂肪性肝病

李娟,
张岭漪

兰州大学第二医院肝病科甘肃省消化肿瘤重点实验室

基金项目:

甘肃省科学事业费科技项目(QS012-C33-41)；

详细信息

中图分类号: R575.5
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出版历程
- 出版日期: 2011-08-20

Vascular endothelial growth factor and nonalcoholic fatty liver disease

Research funding:

摘要

摘要: 非酒精性脂肪性肝病(NAFLD)是影响公共健康的全球性疾病,其病理变化可向非酒精性单纯性脂肪肝(NAFL)、脂肪性肝炎(NASH)甚至脂肪性肝硬化(FLC)发展。虽然NAFLD的这些病理进展机制尚未明确,但仍有一些实验研究提示了可能的诱发机制。其中血管内皮生长因子(VEGF)在促进NAFLD肝脏炎症、肝纤维化中发挥着重要的作用。本文就VEGF与NAFLD关系的研究进展予以综述。
- 血管内皮生长因子类 /
- 脂肪肝
Abstract: Nonalcoholic fatty liver disease (NAFLD) is a prevalent public health problem worldwide, whose pathologic changes are considered to cover a spectrum of disease activity including nonalcoholic fatty liver (NAFL) , nonalcoholic steatohepatitis (NASH) and even fatty liver cirrhosis (FLC) .Although the mechanism from NAFL to FLC has still been unclear, some researches showed the possible inducement mechanism, among which vascular endothelial growth factor (VEGF) playing a key role in promoting the liver inflammation and fibrosis of NAFLD.This article will review the recent findings concerning the relationship between VEGF and NAFLD.
- vascular endothelial growth factors /
- fatty liver

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参考文献(20)

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