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Analysis of the therapeutic effect of elevation of retention enema of herbal drugs by sequential colon dialysis on in patients with acute on chronic hepatic failure
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摘要: 目的探讨结肠透析机中药保留高位灌肠治疗慢性乙型肝炎肝衰竭早期的临床疗效。方法 40例慢性乙型肝炎肝衰竭早期中医属湿热发黄证患者随机分为两组,内科综合用药组(对照组)20例;结肠透析中药组(治疗组)20例。对照组患者给予常规内科综合治疗;治疗组在内科综合治疗基础上予结肠透析机中药保留高位灌肠,每日一次,疗程两周。治疗前及治疗两周后比较临床转归、消化系症状与黄疸明显改善时间、好转与未好转患者血清总胆红素、凝血酶原活动度等相关指标。结果结肠透析治疗组好转率为65%,与内科综合用药的40%比较,其差异有统计学意义(P<0.05)。在好转患者中,结肠透析中药组消化系症状如腹胀、纳差明显改善时间,黄疸消退、TBil下降时间均少于内科综合用药组,差异有统计学意义(P<0.05)。在未好转患者中PTA的下降幅度却明显低于内科综合用药组,其差异有统计学意义(P<0.05)。结论对于肝衰竭早期属湿热瘀黄证患者,在内科综合治疗的基础上,予以结肠透析机中药保留高位灌肠能够提高疗效。Abstract: Objective To observe the clinical effect of Elevation retention enema of herbal drugs by sequential colon dialysis on in patients with acute or chronic hepatic failure in the early stage.Methods Forty cases-of shireyuhuang-syndrome, with acute or chronic hepatic failure associated with hepatitis B virus infection were randomly divided into two groups: treatment group (n=20) and control group (n=20) .The control group underwent comprehensive management of hepatic failure, while the treatment group underwent elevation retention enema of herbal drugs along with the basic of comprehensive management of hepatic failure, one time each day and lasting for 2 weeks.The improvement rate and deterioration rate, the clinical symptoms, the decrease in icterus index, the fall in total bilirubin (TBil) and the rise in prothrombin activity (PTA) were compared between the two groups.Results The total improvement rate was 65% in the treatment group and 40% in the control group with significant difference (P<0.05) ;and the improvement of clinical symptoms, the fall in TBil, and the elevation of PTA in the treatment group were better than those in the control group (P<0.05) .Conclusion Elevation retention enema of herbal drugs by sequential colon dialysis can increase the therapeutic effect on in patients with acute or chronic hepatic failure in the early stage.
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Key words:
- liver failure /
- hepatitis B /
- chronic /
- dialysis /
- colon dialysis
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