Combination of traditional Chinese medicine and western medicine in the treatment of liver cancer
-
摘要: 中医和西医在肿瘤治疗方面各有优势,西医注重消灭肿瘤,而中医则注重调变肿瘤和机体。肝癌治疗方面,中医适合于不能耐受手术/介入疗法患者,作为姑息性治疗,以改善生活质量,延长带瘤生存;作为其他疗法的辅助治疗,达到促进治疗后的恢复,减少复发转移、延长生存期。实验研究发现,5味中药的"松友饮"可通过抑制血管生成、降低肿瘤侵袭,可减少化疗和姑息性切除后的转移,并延长荷瘤鼠生存期,提示这方面中西医结合的可能性。临床实践中需要重视中医理论,而不仅仅是中药的应用;研究中创建中西医结合研究平台则刻不容缓。Abstract: Traditional Chinese medicine (TCM) and western medicine have their own priorities in the cancer treatment and they focus on tumor eradication and tumor-host modulation, respectively.As a palliative treatment, TCM is a choice for the liver cancer patients who could not tolerate surgery or interventional therapies and aims to improve their life quality and prolong their life time.In the adjuvant context, TCM could help patients to recover after other therapies, to minimize disease recurrence, and to prolong patient's survival time.Our experimental studies revealed that a 5-herbal compound "Songyou Yin" could decrease tumor metastasis after chemotherapy or palliative resection and could prolong the life time of tumor-bearing mice by antiangiogenic and anti-invasive mechanisms.In clinical practice, we should pay attention not only to the usage of traditional Chinese drug but also to the theory of TCM.The establishment of the platform of combination of TCM and western medicine is also in need.
-
Key words:
- liver neoplasms /
- TCM WM therapy
-
[1]Zhang XW, Yan XJ, Zhou ZR, et al.Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML[J].Science, 2010, 328 (5975) :240-243. [2]Huang XY, Wang L, Huang ZL, et al.Herbal extract"Songyou Yin"inhibits tumor growth and prolongs survival in nude mice bearing human hepatocellular carcinoma xenograft with high metastatic potential[J].J Cancer Res Clin Oncol, 2009, 135 (9) :1245-1255. [3]Huang XY, Huang ZL, Wang L, et al.Herbal compound"Songyou Yin"reinforced the ability of interferon-alfa to inhibit the enhanced metastatic potential induced by palliative resection of hepatocellular carcinoma in nude mice[J].BMC Cancer, 2010, 10:580. [4]Xiong W, Ren ZG, Qiu SJ, et al.Residual hepatocellular carcinoma after oxaliplatin treatment has increased metastatic potential in a nude mouse model and is attenuated by Songyou Yin[J].BMC Cancer, 2010, 10:219.
本文二维码
计量
- 文章访问数: 3608
- HTML全文浏览量: 26
- PDF下载量: 935
- 被引次数: 0