3.0T磁共振弥散加权成像在肝脏局灶性病变中的诊断价值初探

封海龙; 李彩英; 王英杰; 冯平勇; 崔彩霞

3.0T磁共振弥散加权成像在肝脏局灶性病变中的诊断价值初探

1. 河北省直属机关第二门诊部放射科
2. 河北医科大学第二医院医学影像科

基金项目:

河北省2010年医学科学研究重点课题计划(20100214)；

详细信息

中图分类号: R575;R445.2
计量
- 文章访问数: 2686
- HTML全文浏览量: 9
- PDF下载量: 880
- 被引次数: 0
出版历程
- 出版日期: 2011-04-20

Contribution of diffusion weighted MR imaging in the differential diagnosis of focal hepatic lesions at 3T

Research funding:

摘要

摘要: 目的初步探讨3.0T磁共振弥散加权成像（DWI）对肝脏局灶性病变的鉴别诊断价值。方法采用GE 3.0T Signal EXCITE超导型磁共振扫描系统对65例共68个病灶患者行DWI,并分析病灶信号特征。肝囊肿13个病灶,肝血管瘤12个病灶,炎性假瘤4个病灶,局灶性结节性增生（FNH）5个病灶;肝细胞癌13个病灶,转移瘤21个病灶。应用弥散敏感系数b值0、500、1000 s/mm2的图像拟合出ADC图并测量ADC值。结果肝囊肿、血管瘤、炎性假瘤、FNH、肝细胞癌、转移瘤平均ADC值（×10-3mm2/s）分别为3.34±0.45、2.07±0.35、1.59±0.16、1.50±0.18、1.25±0.31、1.04±0.20;肝囊肿、血管瘤与其它病灶平均ADC之间差异均有统计学意义（P<0.05）。随着b值的增加,肝囊肿信号衰减最明显,肝细胞癌、转移瘤信号衰减不明显。结论 3.0T磁共振弥散加权成像及其定量ADC值对肝脏占位病变的鉴别诊断具有重要的临床价值。
- 肝疾病 /
- 磁共振成像
Abstract: Objective To evaluate the value of diffusion weighted imaging (DWI) in differential diagnosis of focal hepatic lesions.Methods a total of 68 lesions in 65 patients were evaluated, DWI with b=0, 500, 1000s/mm2 was performed on GE Signal EXCITE at 3.0T.Apparent diffusion coefficient (ADC) values were measured in 13 hepatic cysts, 12 hemangiomas, 4 inflammatory pseudotumor, 5 FNH, 13 hepatocellular carcinoma (HCC) , 21metastases.And the signature analysis of lesions were performed simultaneously.Results The mean ADC (×10-3mm2/s) value of cysts was 3.34±0.45, hemangiomas 2.07±0.35, inflammatory pseudotumor 1.59±0.16, FNH 1.50±0.18, HCC 1.25±0.31, metastases 1.04±0.20;hepatic cysts and hemagiomas were easily distinguished from other lesions (P<0.05) ;the signal intensity of cysts decreased obviously with the b value being large, on the contrary, the signal intensity of HCC and metastases decreased poorly.Conclusion DWI is useful for differential diagnosis of focal hepatic lesions clinically.
- liver diseases /
- magnetic resonance imaging

HTML全文

参考文献(8)

[1]Guo Y, Cai YQ, Cai ZL, et al.Diffusion of clinically benignand malignant breast lesions using diffusion-weightedimaging[J].Magn Reson Imaging, 2002, 16 (2) :172-178.

[2]郭友.平面回波技术在腹部的临床应用[J].放射学实践, 2003, 18 (1) :73-75.

[3]Hori M, Ichikawa T, Sou H, et al.Improving diffusion-weighted imaging of liber with SENSE technique:apreliminary study[J].Nippon igaku hoshasen gakkai zasshi, 2003, 63 (4) :177-179.

[4]祝新, 王德抗, 朱斌.SENSE基础上扩散加权成像诊断肝占位性病变的价值[J].放射学实践, 2005, 20 (5) :377-380.

[5]Taouli B, Valerie V, Erik D, et al.Evaluation of liver diffusionisotropy and characterization of focal hepatic lesions with twosingle shot echo-planar MR imaging sequences:prospectivestudy in 66 patients[J].Radiology, 2003, 226 (1) :71-78.

[6]Bruegel M, Holzapfel K, Gaa J, et al.Characterization offocal liver lesions by ADC measurements using a respiratorytriggered diffusion-weighted single-shot echo-planar MRimaging technique[J].Eur Radiol, 2008, 18 (3) :477-485.

[7]郑晓林, 徐辉雄, 吕明德, 等.扩散加权MRI定性诊断肝脏局灶性病变的研究[J].中华放射学杂志, 2005, 39 (2) , 173-176.

[8]Erturk SM, Ichikawa T, Sano K, et al.Diffusion-weightedmagnetic resonance imaging for characterization of focalliver masses:impact of parallel imaging (SENSE) and bvalue[J].J Comput Assist Tomogr, 2008, 32 (6) :865-871.

施引文献

资源附件(0)

访问统计