Predicting scoring system for hepatocellular carcinoma development in chronic hepatitis B patients
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摘要: <正>在亚洲,慢性乙型肝炎(CHB)是肝癌(HCC)的主要病因。尽管在根治性治疗上已取得巨大进展,但由于许多HCC患者已进展至晚期,癌症病死率仍然较高。为防止这一致死性疾病,有两种潜在的策略:(1)提供治疗以降低HCC发病率;(2)早期发现HCC。
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Key words:
- hepactitis B /
- chronic
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[1]Chan HL, Sung JJ.Hepatocellular carcinoma and hepatitis Bvirus[J].Semin Liver Dis, 2006, 26 (2) :153-161. [2]Limquiaco JL, Wong GL, Wong VW, et al.Evaluation ofmodel for end stage liver disease (MELD) -based systemsas prognostic index for hepatocellular carcinoma[J].JGastroenterol Hepatol, 2009, 24 (1) :63-69. [3]Liaw YF, Sung JJ, Chow WC, et al.Lamivudine for patientswith chronic hepatitis B and advanced liver disease[J].NEngl J Med, 2004, 351 (15) :1521-1531. [4]Wong VW, Wong GL, Chim AM, et al.Surrogate end pointsand long-term outcome in patients with chronic hepatitisB[J].Clin Gastroenterol Hepatol, 2009, 7 (10) :1113-1120. [5]Sung JJ, Tsoi KK, Wong VW, et al.Meta-analysis:Treatment ofhepatitis B infection reduces risk of hepatocellular carcinoma[J].Aliment Pharmacol Ther, 2008, 28 (9) :1067-1077. [6]Wong GL, Wong VW, Tan GM, et al.Surveillance programmefor hepatocellular carcinoma improves the survival of patientswith chronic viral hepatitis[J].Liver Int, 2008, 28 (1) :79-87. [7]Zhang BH, Yang BH, Tang ZY.Randomized controlled trialof screening for hepatocellular carcinoma[J].J Cancer ResClin Oncol, 2004, 130 (7) :417-422. [8]Wong VW, Chan SL, Mo F, et al.Clinical scoring systemto predict hepatocellular carcinoma in chronic hepatitis Bcarriers[J].J Clin Oncol, 2010, 28 (10) :1660-1665. [9]Mok TS, Yeo W, Yu S, et al.An intensive surveillanceprogram detected a high incidence of hepatocellularcarcinoma among hepatitis B virus carriers with abnormalalpha-fetoprotein levels or abdominal ultrasonographyresults[J].J Clin Oncol, 2005, 23 (31) :8041-8047. [10]Chan HL, Hui AY, Wong ML, et al.Genotype C hepatitisB virus infection is associated with an increased risk ofhepatocellular carcinoma[J].Gut, 2004, 53 (10) :1494-1498.
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