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关于肝癌治疗的策略

汤钊猷

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关于肝癌治疗的策略

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  • 中图分类号: R735.7

Treatment strategies for liver cancer

  • 摘要: 近年肝癌各种疗法的5年生存率已接近高限,瓶颈主要是转移复发。20世纪肝癌治疗均以消灭肿瘤为目标,近年已转变为消灭和改造并举。在消灭肿瘤的基础上,出现了多种调变残癌和调变机体的办法,如合并应用细胞因子、抗炎剂、分子靶向治疗剂、全身性干预以及中医中药等。还出现了一些潜在的治疗途径,如小RNA等,一些"无关药物"(如治疗结核病的利福平)也可望用于肝癌治疗。实验研究表明,常规疗法常通过上皮-间质转化而促进转移,研究其干预是提高现有疗法疗效的一条捷径,但同时需要提防"过度治疗"。总之,消灭肿瘤仍然是基本的,而调变肿瘤和机体则是重要的补充。

     

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  • 出版日期:  2011-04-20
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