抗肝纤维化治疗研究的若干问题

蔡卫民

抗肝纤维化治疗研究的若干问题

蔡卫民

浙江大学医学院附属第一医院传染病研究所传染病诊治国家重点实验室

详细信息

中图分类号: R575.2
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出版历程
- 出版日期: 2011-03-20

Some problems in anti-fibrotic therapies

Cai WeiMin

摘要

摘要: 目前全球都较重视抗肝纤维化的研究,介绍抗肝纤维化治疗的靶点,讨论如何在临床前通过体外和体内模型筛选出有效的抗肝纤维化药物。回顾抗肝纤维化药研究进展,总结临床研究的要求与存在的困难。
- 肝硬化 /
- 肝炎,慢性
Abstract: More and more research focuses on the anti-fibrotic therapy worldwide.The purposes of this review are to introduce the therapy targets of anti-fibrosis,discuss how to perform preclinical screening and effective development of anti-fibrotic drugs based on the in vitro and in vivo models,the progress of anti-fibrosis by chemical compounds and the summary of the demand and problems exist in clinical validation.
- liver cirrhosis /
- hepatitis

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参考文献(46)

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