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丙型肝炎病毒感染者的血清甘露聚糖结合凝集素分析

郭玲 赵梅桂 张荣

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丙型肝炎病毒感染者的血清甘露聚糖结合凝集素分析

详细信息
  • 中图分类号: R512.63

  • 摘要: 目的分析丙型肝炎病毒(HCV)感染者的血清甘露聚糖结合凝集素(MBL),探讨血清MBL水平与HCV感染及其致病程度的关系。方法收集HCV感染者128例,分成HCV携带者、轻度慢性丙型肝炎患者和中度慢性丙型肝炎患者三组。通过酶联免疫吸附法测定血清MBL的水平。结果HCV感染者血清MBL浓度均值为(1.729±0.529)μg/ml,高于正常对照组均值(0.974±0.305)μg/ml(P<0.01),且血清MBL水平随患者肝功能损害程度加重而增加。结论作为急性时相反应蛋白,血清MBL可反应HCV感染导致的慢性病理状态,它可能也参与肝脏纤维化的过程。

     

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  • 出版日期:  2009-05-20
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