左卡尼汀联合多烯磷脂酰胆碱治疗非酒精性脂肪性肝炎的疗效观察

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左卡尼汀联合多烯磷脂酰胆碱治疗非酒精性脂肪性肝炎的疗效观察

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山东省济宁市第二人民医院

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中图分类号: R575.1
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出版历程
- 出版日期: 2009-04-20

Dong Kun

摘要

摘要: 目的评价左卡尼汀联合多烯磷脂酰胆碱治疗非酒精性脂肪性肝炎的疗效。方法将82例非酒精性脂肪性肝炎患者随机分为两组,试验组41例联合服用左卡尼汀联合多烯磷脂酰胆碱,对照组41例单用多烯磷脂酰胆碱为对照组。疗程均为12周。治疗前后测定血清转氨酶、血脂水平及肝/脾CT比值。结果治疗后试验组血清转氨酶、血脂下降明显,肝/脾CT比值升高显著,与对照组比较差异有统计学意义(P<0.05)。结论左卡尼汀联合多烯磷脂酰胆碱治疗非酒精性脂肪性肝炎具有良好的效果,值得临床应用。
- 非酒精性脂肪性肝炎 /
- 左卡尼汀 /
- 多烯磷脂酰胆碱
Abstract: Objective To evaluate the clinical efficacy of Levocarnitine combined with Polyene Phosphatidylcholine in treatment of nonalcoholic steatohepatitis.Methods A total of 82 patients with nonalcoholic steatohepatitis were selected and divided randomly into two groups..In experiment group, the patients received Levocarnitine combined with polyene Phosphatidylcholine (n=41) for 12 weeks.While in control group the patients received Polyene Phosphatidylcholine oniy (n=41) for 12 weeks.The levels of serum transaminase, blood grease and liver/spleen CT index were measured before and after treatment respectively.Results The levels of serum transaminase and blood grease in experiment group were decreased obviously after treatment.Meanwhile liver/spleen CT index were increased obviously after treatment.There were a significant differece between the two groups (P<0.05) .Conclusion Treatment with Levocarnitine combined with polyene Phosphatidylcholine was an effective remedy for treating nonalcoholic steatohepatitis.It was worth of clinic application.
- nonalcoholic steatohepatitis /
- levocarnitine /
- Polyene phosphatidylcholine.

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参考文献(7)

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