奥曲肽联合硝酸甘油治疗肝硬化静脉曲张出血的疗效分析

向志勇; 郑勇; 徐丽红; 李睿; 周婷; 杨远; 杨小艳

奥曲肽联合硝酸甘油治疗肝硬化静脉曲张出血的疗效分析

1. 石河子大学医学院第一附属医院消化内科
2. 石河子大学医学院第一附属医院医学实验室
3. 石河子大学医学院第一附属医院老年病科

详细信息

中图分类号: R575.2
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出版历程
- 出版日期: 2009-03-20

摘要

摘要: 目的观察奥曲肽联合硝酸甘油对肝硬化静脉曲张出血患者的疗效。方法选择120例肝硬化静脉曲张患者,随机分为二组,治疗组60例,给予奥曲肽联合硝酸甘油为主的治疗,对照组60例给予以奥曲肽为主的治疗。治疗2周,观察其疗效。结果治疗前后两组患者门静脉血流量的降低值和脾静脉血流量降低值比较有显著性差异;两组治愈率,平均止血时间及疗效差别比较具有统计学意义(P<0.05)。结论奥曲肽联合硝酸甘油治疗组治疗肝硬化静脉曲张出血的疗效优于单用奥曲肽的治疗组。
- 肝硬化静脉曲张 /
- 奥曲肽 /
- 硝酸甘油
Abstract: Objective To observe the clinical effectiveness of combining glyce-rol trinitrate and octreotide for the treatment of liver cirrhosis varicosis hemorrhage.Methods one hundred and twenty (120) patients with liver cirrhosis and varicosis hemorrhage were randomized allocated into two groups.Treatment group: 60 patients, combining glycerol trinitrate and octreotide for the treatment of liver cirrhosis and varicosis hemorrhage.Control group: 60 patients, with octreotide for the treatment of liver cirrhosis and varicosis hemorrhage.two weeks were one course of treatment.Results Significant difference were exhibited between the treatment group and control group patients' step down value of the blood flow of portal vein and splenic vein.with cure rate and average haemostasis time, significant difference were exhibited between two groups (P<0.05) .Conclusion combining glycerol Trinitrate and octreotide forthe patients with liver cirrhosis and varicosis hemorrhage showed a better result.
- Liver cirrhosis varicosis /
- Octreotide /
- Glycerol trinitrate

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参考文献(10)

[1]叶任高, 陆再英.内科学[M].北京:人民卫生出版社, 2004∶448.

[2]杨冬华, 陈湖.消化系疾病治疗学[M].北京:人民卫生出版社, 2005∶98.

[3]Moriyashi F.Measurement of portal vascular resistance in patient swith portal hypertension[J].Gastroenterology, 2004, 90 (3) ∶710.

[4]谢渭芬, 曾欣.食管胃底静脉曲张出血的防治[J].国外医学.消化系疾病分册, 2004, 24 (3) ∶131-134.

[5] 姒健敏, 王良静.食管静脉曲张内镜治疗现状及评价[C].浙江省消化专题会议, 2005∶11-13.

[6] 叶任高, 陆再英.内科学[M].北京:人民卫生出版社, 2004∶440-442.

[7]刘祖炳.奥曲肽和洛赛克治疗肝硬化静脉曲张破裂出血65例观察[J].浙江临床医学, 2008, 10 (4) ∶535-536.

[8] 谢渭芬, 曾欣.食管胃底静脉曲张出血的防治[J].国外医学.消化系疾病分册, 2004, 24 (3) ∶131-134.

[9]Ziol M, Handra2Luca A, Kettaneh A, et al.Noninvasive assessmentof liver fibrosis by measurement of stiffness in patient swit h chronichepatitis C[J].Hepatology, 2005, 41∶48-54.

[10]骆丹东.奥美拉唑和奥曲肽联合治疗肝硬化并上消化道出血疗效观察[J].江西医药, 2005, 40 (1) ∶55-56.

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