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恩替卡韦治疗乙肝相关性肾炎临床观察

阚晓 史兆章 郑兆敏 韩邵磊

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恩替卡韦治疗乙肝相关性肾炎临床观察

详细信息
  • 中图分类号: R692.3

The effect of Entikawei in the treatment of hopatitis B virus associated glomerulonephritis (HBV-GN)

  • 摘要: 目的探讨恩替卡韦治疗乙肝相关性肾炎(HBV-GN)的疗效。方法78例患者,临床诊断为乙肝相关性肾炎,随机分为二组。治疗组在综合治疗基础上口服恩替卡韦0.5mg,qd;对照组除不用恩替卡韦,余同治疗组。三个月后分别观察肝肾功能、HBV-M和HBVDNA等变化。结果治疗组在改善肝肾功能及HBeAg和HB-VDNA阴转率诸方面较对照组有显著性差异。结论乙肝相关性肾炎与原发性肾小球疾病的临床表现类似,恩替卡韦对治疗乙肝相关性肾炎有非常好的疗效。

     

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  • 出版日期:  2008-06-20
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