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The relevance among HBV DNA in serum, in liver tissue and hepatitis indexes of patients with hepatitis B.
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摘要: 目的探讨慢性乙型肝炎患者血清HBV DNA与肝组织HBV DNA及其肝脏炎症指标的相关性。方法随机选择慢性乙肝患者51例做血液HBV DNA检测,并行肝穿刺取肝组织,分别进行肝组织HBV DNA检测及组织学检测。结果慢性乙型肝炎患者肝组织HBV DNA检出率明显高于血清内,肝组织内HBV DNA含量明显高于血液内。结论乙型肝炎患者血清HBV DNA与肝脏炎症程度无显著性差异,无相关性,不能真实反映肝组织内HBV DNA感染及复制情况。肝组织内HBV DNA与肝脏炎症程度有显著性差异,呈反向相关。Abstract: Objective Discuss the relevance among HBV DNA in serum, in liver tissue and hepatitis indexes of patients with chronic hepatitis B.Methods choose 51 patients with chronic hepatitis B randomly, then take blood out to have HBV DNA examination and puncture the liver tissue, have HBV DNA of liver tissue detect and histology detect separately.Results HBV DNA positive of blood is apparently higher than it in serum, HBV DNA content in liver tissue is apparently higher than it in blood.Conclusions There is no significant difference and relevance between hepatitis B patients and the serious degree of hepatitis, it can not show the infection of difference between HBV DNA of liver tissue and the serious degree of hepatitis, the relationship of the two is opposite relevance.
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Key words:
- hepatitis B /
- liver tissue /
- hepatitis /
- relevance /
- HBVDNA
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