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Serum C3、C4 levels in patients with hepatitis B
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摘要: 目的探讨乙型病毒性肝炎(简称乙肝)患者血清补体C3(C3)、补体C4(C4)的临床意义。方法检测59例乙肝患者的血清C3、C4浓度,据病情分成三组,与对照组进行组间比较。结果除急性肝炎组C4与对照组无显著差异外,其他病例组C3、C4浓度均较对照组明显下降,以重型肝炎最为明显。结论提示C3、C4的检测对乙肝患者病情评估和预后判断有重要意义。Abstract: Objective To evaluate the serum C3、C4 levels in patients with hepatitis B.Methods 59 cases with hepatitis B were reviewed, their serum C3、C4 levels were measured.They were divided into different group according to pathogenetic condition.Their serum C3、C4 levels were compared with control group and with each others.Among 59 cases, They were divided into 3 group:group A (acute hepatitis B) contained 17 cases, group B (chronic hepatitis B) contained 30 cases, group C (serious hepatitis B) contained 12 cases.Group D (control group) contained 16 cases.Results There was no different in serum C4 levels in group A and group D (P<0.05) , others were significant different in both serum C3 and C4 (P<0.05) .The extent of serum C3 and C4 descend was correlated to degree of hepatic injury and immunologic function.Conclusion Serum C3 and C4 levels were important indexes to evaluate the liver function of patients with hepatitis B.It was close correlated to pathogenetic condition.
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Key words:
- virus hepatitis /
- complement /
- serum /
- liver function
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[1]Wang JY, Wang XL, Liu P.Detection of serum TNF-α, IFN-γ, IL-6 and IL-8 in patients with hepatitis B[J].World GastroenterolJ, 1999, 5 (1) ∶38-40. [2]余红岚, 刘若英, 宋静芳, 等.病毒性乙型肝炎患者Th细胞亚群与ALT、IgG、C3的相关性研究[J].贵阳医学院学报, 2004, 29 (2) ∶118-121. [3]龚非力.医学免疫学[M].第二版.北京:科学出版社, 2004∶42-59. [4]高美华, 许化溪.医学免疫学[M].北京:人民军医出版社, 1999∶62. [5]邹焕荣, 张旭, 何国坚, 等.乙型肝炎患者血清补体C3含量的分析[J].国际医药卫生导报, 2004, 10 (2-3) (下半月刊) ∶61-62. [6]毛远丽, 王海滨, 孙志强, 等.慢性肝炎患者ECR1基因多态性、数量及活性的变化[J].中华实验和临床病毒学杂志, 2003, 17 (2) ∶146-148. [7]韦丽霞, 唐任光, 杨柳, 等.免疫球蛋白及补体检测在肝炎诊断中的意义[J].右江民族医学院学报, 2006, 28 (2) ∶266-267. [8] 李伟, 陈益平, 汪洪娇.血清补体C3、C4水平与儿童慢性乙肝的临床关系[J].温州医学院学报, 2002, 32 (5) ∶317-318. [9]张占卿, 董华娟, 王冯滨, 等.亚急性重型肝炎早期外周血免疫学指标改变的特点及其意义[J].世界感染杂志, 2004, 4 (4) ∶350-353. [10] 迟丽娜, 黄俊佩.重型肝炎患者IgA、IgG、IgM、C3检测的临床意义[J].中西医结合肝病杂志, 2002, 12 (4) ∶220. -
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