Study on prognostic factors of chronic severe hepatitis B.
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摘要: 目的总结426例慢性重型肝炎病例的预后因素。方法采用Logistic多元回归分析,筛选出年龄、肝硬化Ch ild-Pugh分级、败血症、肝肾综合征、重型肝炎分期、消化道出血为影响预后的独立危险因素;根据各自相关系数构建评估方程,将原始数据代入公式。结果两组患者分值差异显著(P<0.001),以0.5为判别界限,好转组临床符合率84.3%,无效组临床符合率95.5%。结论评估方程可较好地评估预后,对指导临床选择治疗方法有一定价值。Abstract: Objective Clinical data from 426 patients suffering from chronic severe hepatitis B were analyzed by logistic regression analysis.Methods It was showed that age, classification of Child-Pugh in hepatic cirrhosis, hematosepsis, hepatorenal syndrome, stages in severe hepatitis and gastrointestinal hemorrhage are independent risk factors related to prognosis;the evaluation equation for assessment of the prognosis was built up by correlative coefficient respectively.Results The scoring system gives different scores between the effective treatment group and ineffective treatment group with statistical significance (P<0.01) when clinical data of patients was used.If we take 0.5 as the limit, the coincidence rate of the effective treatment group is 84.3%, the ineffective treatment group io 95.5%.Conclusion The evaluation equation is very effective in evaluating the prognosis and is valuable in guiding treatment.
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Key words:
- chronic severe hepatitis B /
- prognosis
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