-
-
[1]James O, Day C.Non-alcoholic steatohepatitis∶another disease of af-fluence[J].Lancet, 1999, 353 (9165) ∶1634-1636. [2]Day CP, James OF.Steatohepatitis∶a tale of two“hit”[J]?Gastroen-terology, 1998, 114 (4) ∶842-845. [3]Lisa O Rourke, Steven J, Yeaman, et al.Insulin and leptin acutely reg-ulate cholesterol ester metabolism in macrophages by novel signaling Path-ways[J].Diabetes, 2001, 50 (50) ∶955-961. [4]Koteish A, Diehl AM.Animal models on steatosis[J].Sem Liv Dis, 2001, 21 (1) ∶89-104. [5]Shimomura 1, Hammer RE, Lkemoto S, et al.Leptin reverses insulinsesistance and diabetes mellitus in mice with congenital lipodystrophy[J].Nature, 1999, 401 (2) ∶72-76. [6]Jaro JF, Kolaczynski JW, Nyce MR, et al.Decreased cerebrospinal-fluid/serum leptin ratio inobesity∶a possible mechanism for leptin resis-tance[J].Lancet, 1996, 348 (9021) ;159-161. [7]Uygun A, kadayifci A, Yesilova Z, et al.Serum leptin levels in patientswith nonalcoholic teatohepatitis[J].Am J Gastroenterol, 2000, 95 (12) ∶3584-3589. [8]Unger RH, Zhou YT, Orci L.Regulation of fatty acid homeostasis incells∶Novel role of leptin[J].Proc Natl Acad Scio USA, 1999, 96 (5) ∶2327-32. [9]Taylor SI, Barr V, Reitman M.Does leptin contribute to diabetes causedby obesity[J].Science, 1996, 15∶274 (5290) ∶1151-152. [10]Marchesini G, Brizi M, Morselli-Labate AM, et al.Association of non-alcoholic fatty liver disease with insulin resistance[J].Am J Med, 1999, 107 (5) ∶450-455. [11]Lin HZ, Yang SQ, Chuckaree C, et al.Metformin treatment reversesfatty liver disease in obese leptin-deficient mice[J].Nature Med, 2000, 6 (9) ∶998-1003. [12]Cohen B, Novick D, Rubinstein M.Modulation of insulin activity byleptin[J].Science, 1996, 274 (5290) ∶1185-1188. [13]巫协宁.瘦素、肿瘤坏死因子和脂肪肝病[J].肝脏, 2002, 7 (4) ∶271-272. [14]Faggioni R, Jones-Carson J, Reed DA, et al.Leptin deficient (ob/ob) mice are protected from T-cell mediated hepatotoxicity∶role of tumornecrosis fator alpha and IL-18[J].Prot Natl Acad Sci USA, 2000, 97 (5) ∶2367-2372. [15]Potter JJ, Vomack L, Mezey E, et al.Transdifferentiation of rat hepaticstellate cells results in leptin expression[J].Biochem Biophys Res Com-mun, 1998, 244 (1) ∶178-182. [16]Tiomthy JTJ, Kieffer RS, Holler CA, et al.Leptin suppression of in-sulin secretion by the activation of ATP-sensitive K+channels in pan-creaticβ-cells[J].Diabetes, 1997, 46 (6) ∶1087-1093. [17]Kamohara S, Barcelin R.Halaas JL, et al.Acute stimulation of glucosemetabolism in mice by leptin treatment[J].Nature, 1997, 389 (6649) ∶374-377. [18]Considine RV, Sinha MK, Heiman ML, et al.Serum immunoreactive-leptin concentrations in normal-weight and obesehumans[J].N Engl JMed, 1996, 334 (5) ∶292-296.
本文二维码
计量
- 文章访问数: 3033
- HTML全文浏览量: 3
- PDF下载量: 952
- 被引次数: 0