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Study of the relationship SARS and hepatitis virus B
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摘要: 探讨SARS(重症急性呼吸综合征 )并发肝功能损害及其与乙肝病毒的关系。观察SARS患者 10 8例 ,其中同时有乙肝病毒携带者 38例 (A组 ) ,无任何肝病基础的有 4 6例 (B组 ) ,SARS患者有脂肪肝基础病的有 2 4例 (C组 ) ,比较各组SARS患者肝损害的程度以及乙肝病毒变异的关系。有乙肝病毒 (HBV)携带的SARS患者肝损害的程度显著高于无HBV感染者 ,同时并发重症肝炎的机率明显增高 ,在乙肝病毒携带者感染SARS病毒后极易诱发病毒野生株增多。有脂肪肝基础的SARS患者和无脂肪肝患者肝损害无显著差异。有乙肝病毒感染或病毒携带者的SARS患者需密切观察肝功能积极防治急性肝细胞坏死Abstract: To study the connection between SARS (severe acute respiratory syndrome) complicated liver functional injury and hepatitis virus B. We observed 108 cases of SARS patients:38 cases with hepatitis virus B (A group) , 46 cases without any liver diseases (B group) , 24 cases with fatty liver (C group) . Then compared the relationship between the degree of liver injury and the variation of hepatitis virus B. The results showed that the degree of liver injury in SARS patients with hepatitis virus B was higher than that in SARS patients without hepatitis virus B. In the same time, the incidence of complicated severe hepatitis was higher too. The activation of viral wild strains was easier in SARS patients with hepatitis virus B. There was no evident difference between patients with fatty liver and without fatty liver. Therefore, we should observe the liver function of the SARS patients with hepatitis B more carefully, prevent and treat their acute hepatic cell necrosis.
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Key words:
- SARS /
- hepatitis virus B
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