Study on relationship between sICAM-1、IL-18 level changes in sera of the patients with chronic hepatitis B
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摘要: 检测慢性乙型肝炎 (CHB)患者血清可溶性细胞间粘附分子 - 1(sICAM - 1)、白细胞介素 18(IL - 18)水平 ,探讨sICAM - 1、IL - 18变化规律及临床意义。采用ELISA法对慢性乙型肝炎患者血清sICAM - 1、IL - 18水平进行测定。慢性乙型肝炎患者血清sICAM - 1、IL - 18水平明显高于健康对照组 ;且二者呈正相关。sICAM - 1、IL - 18可能参与慢性肝炎的损伤过程
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关键词:
- 慢性乙型肝炎 /
- 血清可溶性细胞间粘附分子-1 /
- IL-18
Abstract: To investigate the changes and clinical significances of serum sICAM-1 and IL-18 levels in the patients with chronic hepatitis B. The sICAM-1 and IL-18 levels in serum of the patients with chronic hepatitis B were detected by ELISA. The sICAM-1 and IL-18 levels were significantly higher than those of healthy groups. Moreover, there was a close positive correlation between sICAM-1 and IL-18. The sICAM-1 and IL-18 may participate in liver inflammatory injury process.-
Key words:
- Chronic hepatitis B /
- sICAM-1 /
- IL-18
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