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The expression and significance of chemokine interferon-inducible protein-10 (IP-10) in chronic hepatitis B patients
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摘要: 为探讨趋化因子IP - 10在慢性乙肝患者的表达水平及其与肝细胞受损程度之间的关系 ,分别设立健康对照组 ,慢性乙肝中轻度组、重度组、慢性重型肝炎组 ,采用ELISA方法检测IP - 10、γ -IFN的血清浓度。并同时作常规生化检测。结果慢性乙肝各组IP - 10水平均高于对照组 ,且与ALT、AST呈正相关。表明慢性乙肝患者血清IP- 10水平可反映肝细胞损伤程度Abstract: To clarify the role of IP-10 in Chronic Hepatitis B, we study the serum levels of IP-10 in chronic hepatitis B patients and chronic severe hepatitis patients. The correlation between the serum levels of IP-10 and clinical parameters was also evaluated. The serum levels of IP-10 was much higher in patients with chronic hepatitis B than in healthy controls, and it was significantly correlated with ALT?AST. The results suggest that the serum levels of IP-10 can reflect the damage of hepatocytes.
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Key words:
- Chemokine /
- Interferon-inducible Protein-10 (IP-10) /
- chronic hepatitis B
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