中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

肝癌基因治疗策略

钱学敏

引用本文:
Citation:

肝癌基因治疗策略

详细信息
  • 中图分类号: R735.7

  • [1]Nagy H, Panis Y, Fabre M, et al. Are hepatomas a good target for suicide gene therapy? An experimental study in rats using retroviral-mediated transfer of thymidine kinase gene[J].Surgery, 1998, 123 (1) ∶19-24.
    [2]Kuriyama S, masui K, Kikukawa M, et al. Complete cure of established murine hepatocellular carcinoma is achievable by repeated injections of retroviruses carrying the herpes simplex virus thymidine kinase gene[J].Gene Ther, 1999, 6 (4) ∶525-533.
    [3]Qian C, Idoate M, Bilbao R, et al. Gene transfer and therapy with adenoviral vector in rats with diethylnitrosamine-induced hepatocellular carcinoma[J].Hum Gene Ther, 1997, 8 (3) ∶349-358.
    [4]Kanai F, Shiratori Y, Yoshida T, et al. Gene therapy for a-fetoprotein-producing human hepatoma cell lines by adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene[J].Hepatology, 1996, 23∶1359-1367.
    [5]Block A, Freund CT, Chen SH, et al. Gene therapy of metastatic colon carcinoma: regression of multiple hepatic metastases by adenoviral expression of bacterial cytosine deaminase[J].Cancer Gene Ther, 2000, 7 (3) ∶438-445.
    [6]Kuriyama S, Mitoro A, Yamazaki M, et al. Comparison of gene therapy with the herpes simplex virus thymidine kinase gene and the bacterial cytosine deaminase gene for the treatment of hepatocellular carcinoma[J]. Scand J Gastroenterol, 1999, 34 (10) ∶1033-1041.
    [7]Hirschowitz EA, Naama HA, Evoy D, et al. Regional treatment of hepatic micrometastasis by adenovirus vector-mediated delivery of interleukin-2 and interleukin-12 cDNAs to the hepatic parenchyma[J].Cancer Gene Ther, 1999, 6 (6) ∶491-498.
    [8]Santodonato L, Ferrantini M, Palombo F, et al. Antitumor activity of recombinant adenoviral vectors expressing murine IFN-alpha in mice injected with metastatic IFN-resistant tumor cells[J].Cancer Gene Ther, 2001, 8 (1) ∶63-72.
    [9]He P, Tang ZY, Ye SL, et al. The targeted expression of interleukin-2 in human hepatocellular carcinoma cells[J]. J Exp Clin Cancer Res, 2000, 19 (2) ∶183-7.
    [10]Cao G, Kuriyama S, Tsujinoue H, et al. A noval approach for inducing enhanced and selective transgene expression in hepatocellular-carcinoma cells[J].Int J Cancer, 2000, 87 (2) ∶247-252.
    [11]Martinet O, Ermekova V, Qiao JQ, et al. Immunomodulatory gene therapy with interleukin 12 and 4-1BB ligand:long-term remission of liver metastases in a mouse model[J]. J Natl Cancer Inst, 2000, 92 (11) ∶931-936.
    [12]Sun Y, Qian C, Peng D, et al. Gene transfer to liver cancer cells of B7-1 plus interleukin 12 change immunoeffector mechanisms and suppresses helper T cell type 1 cytokine production induced by interleukin 12 alone[J].Hum Gene Ther, 2000, 11 (1) ∶127-138.
    [13]Su H, Lu R, Ding R, et al. Adeno-associated viral-mediated gene transfer to hepatoma: thymidine kinase/interleukin 2 is more effective in tumor killing in non-ganciclovir (GCV) -treated than in GCV-treated animals[J].Mol Ther, 2000, 1 (6) ∶509-515.
    [14]Xu GT, Sun ZT, Forrester K, et al. Tissue-specific growth suppression and chemosensitivity promotion in human hepatocellular carcinoma cells by retroviral-mediated transfer of the wild-type p53 gene[J].Hepatology, 1996, 24∶1264-1268.
    [15]Mercola D, Coben J. Antisense approaches to cancer gene therapy[J].Cancer Gene Therapy, 1995, 2∶47-59.
    [16]Kang MA, Kim KY, Seol JY, et al. The growth inhibition of hepatoma by gene transfer of antisense vascular endothelial growth factor[J].J Gene Med, 2000, 2 (4) ∶289-96.
    [17]Chen CT, Lin J, Li Q, et al. Antiangiogenic gene therapy for cancer via systemic administration of adenoviral vectors expressing secretable endostatin[J].Hum Gene Ther, 2000, 11 (14) ∶1983-96.
  • 加载中
计量
  • 文章访问数:  2214
  • HTML全文浏览量:  2
  • PDF下载量:  844
  • 被引次数: 0
出版历程
  • 出版日期:  2002-06-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回