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Clinical study of 3-dimensional conformal radiotherapy on primary liver cancer.
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摘要: 探讨立体定向适形放疗在肝癌治疗中的价值。应用 6MVX线直线加速器对 79例中晚期肝癌行适形性放疗。肿瘤靶体积 （GTV）平均 336 4cm3 ,计划靶体积 （PTV）平均 416 5cm3 。单次靶区处方剂量 2Gy～ 10Gy ,隔日一次。总照射剂量平均 38Gy。近期疗效CR 2 4 1%（19/79） ,PR48 1%（38/79） ,NR2 7 8%（2 2 /79） ,总有效率 （CR+PR）为 72 2 %。 1、2、3年生存率分别为 72 1%（5 7/79）、45 9%（2 8/6 1）和 2 0 0 %（8/4 0 ）。放射性肝炎发生率为6 3%（5 /79）。立体定向适形放疗对肝癌具有较好的疗效 ,是一种较好的治疗模式。Abstract: To evaluate the treatment of 3-dimensional conformal radiotherapy (3-DCRT) on primary liver cancer, 79 patients with intermediate and advanced stages liver cancer were treated by 3-DCRT using 6MV X-ray. The mean value of gross target volume (GTV) was 336.4cm 3, and the mean value of planning target volume (PTV) was 416.5cm 3. All patients were given 2Gy～10Gy dose per single target volume, interval 1 day. The mean value of total dose was 38 Gy. Recent retraction rates was CR 24.1% (19/79) , PR48.1% (39/79) , NR27.8% (22/79) , the rate of total validity was (CR+PR) 72.2%. The survival rates at 1?2 and 3 year were 72.1% (57/79) , 45.9% (28/61) and 20.0% (8/40) , radiohepatitis incidence was 6.3% (6/79) . 3-Dimensional conformal radiotherapy has good treatment effect on hepatocarcinoma, which is a good treatmant pattern.
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Key words:
- Liver neoplasms /
- Hepatocarcinoma /
- Radiotherapy /
- 3-Dimensional Conformal Radiotherapy
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[1]胡逸民, 谷铣之适形放射治疗———肿瘤放射治疗技术的进展[J]中华放射肿瘤学杂志, 1997, 6 (1) ∶8～11 [2]扬秉辉, 任正刚, 汤钊猷关于肝癌诊断与分期标准的讨论[J]中华肝脏病杂志, 2000, 8 (3) ∶133～135 [3]ZibariGB , KicheA , ZizziHC , etal.Surgcalandnonsurgicalman agementofprimaryandmetastaticlivertumors[J]AmSurg, 1998, 64 (3) ∶211～220 [4]LawrenceTS , TesserRJ, TenHakenRK .Anapplicarionofdosevolumehistogramstotheireatmentofintraheparicmalignancieswithradiationtherapy[J]IntJRadiatOncolBiolPhys, 1990, 19 (4) ∶1041～7 -
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