IFN-α联合利巴韦林治疗抗HBe阳性慢性乙型肝炎的新疗法及机理

唐宝璋; 燕奎华

IFN-α联合利巴韦林治疗抗HBe阳性慢性乙型肝炎的新疗法及机理

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中图分类号: R512.62
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出版历程
- 出版日期: 2002-03-20

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参考文献(12)

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[3] DavisGL , Esteban-MurR , RustgV , etal.Iterferonalfa-2baloneorincombinationwithribavirinforthetreatmentofrelapseofchronichepatitisC .IternationalHepatitisInternationalTherapyGroup[J]NEnglJMed, 1998, 339∶1493-1499.

[4] PennaA , DelPreteG , CavalliA , etal.PredominantT -helper1cytokineprofileofhepatitisBvirusnucleocapsid-specificTcellsinacuteselflimitedhepatitisB .[J]Hepatology, 1997, 25∶1022-1027.

[5]BertolettiA , D’EliosMM , BoniC , etal.Differentcytokinepro filesofintraphepticTcellsinchronichepatitisBandhepatitisCvirusinfections[J]Gastroenterology, 1997, 112∶193-199.

[6]CotonatT , QuirogaJA , Lopez-AlcorochoJM , etal.Pilotstudyofcombinationtherapywithribavirinandinterferonalfafortheretreat mentofchronichepatitisBeantibody-positive patients[J]Hepatology, 2000, 31∶502-506.

[7]RicoMA , QuirogaJA , SubiraD , etal.HepatitisBvirus-specificT -cellproliferationandcytokinesecretioninchronichepatitisBeantibody-positivepatientstreatedwithribavirinandinterferonal pha[J]Hepatology, 2001, 33 (1) ∶295-330.

[8]OliveriF , SantantonioT , BellatiG , etal.Longtermresponsetotherapyofchronicanti-HBe-positivehepatitisBispoorindepen dentoftypeandscheduleofinterferon[J]AmJGastroenterol, 1999, 94∶1366-1372.

[9] HadziyannisS , BramouT , MakrisA , etal.Interferonalfa-2btreatmentofHBeAgnegative/serumHBVDNApositivechronicac tivehepatitistypeB[J]JHepatol, 1990, 11 (Suppll) ∶133-136.

[10]MartinJ , NavasS , QuirogaJA , etal.Effectsoftheribavirin-in terferonalfacombinationonculturedperipheralbloodmononuclearcellsfromchronichepatitisCpatients[J]Cytokine, 1998, 10∶635-644.

[11] HultgrenC , MilichDR , WeilandO , etal.TheantiviralcompoundribavirinmodulatestheThelper (Th) Th1/Th2subsetbalanceinhepatitisBandCvirus-specificimmuneresponses[J]JGenVirol, 1998, 79∶2381-2391.

[12] LaiCL , ChienRN , LeungNW , etal.Aone-yeartrialoflamivudineforchronichepatitisB .AsiaHepatitisLamivudineStudyGroup[J]NEnglJMed, 1998, 3398.

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