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Clinical significance of serumthyroxine determination in patients with liver cirrhosis
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摘要: 探讨肝硬化患者游离甲状腺原氨酸 (FT3) ,游离甲状腺素 (FT4 )变化及其与临床、实验室检查及肝功能的关系。用放射免疫法测定 2 73例不同程度肝硬化患者FT3、FT4 、TSH水平。随着肝硬化程度加重 ,FT3 及FT4呈下降趋势 ,FT3、FT4 浓度与腹水、血浆白蛋白浓度及肝功能程度密切相关。FT3、FT4 浓度对估计肝硬化严重程度及预后具有实用价值 ,肝硬化低FT3、低FT4 血症可试用甲状腺素治疗。Abstract: The relevant study between serum freetriiodothyronine (FT 3) . Free-thyroxine (FT 4) and clinical manifestation, Laboratory, liver functions in patients with different degree of liver cirrhosis. The concentration of serum FT 3 and FT 4 were determined by radioimmunoassay in 273 patients with different degree of liver cirrhosis. The result showed that the serum FT 3 and FT 4 decreased gradually as the degree of clinical liver cirrhosis deteriorated. There was a significant relation between FT 3. FT 4 and ascites, serum album, liver functions. Measuring the concentration of FT 3. FT 4 has utilizable and reliable clinical value in predicting the degree and prognosis of liver cirrhosis. The liver cirrhosis with low-FT 3 syndrome or low-FT 4 syndrome may try to be treated with thyroxine.
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Key words:
- Liver cirrhosis /
- Free-triiodothyronine /
- Free-thyroxine /
- Liver function
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[1]李秀钧 , 冉兴无 低甲状腺原氨酸、低甲状腺素综合征 [J] 中国实用内科杂志 , 1996 , 16∶75 9 [2 ]夏德全 , 王吉耀 肝硬化 [M ] 见陈灏珠主编 , 实用内科学第 10版 , 北京 , 人民卫生出版社 , 1998∶16 77 [3]JosephM , Tibaldi, M D , andMartinI, etal Effectofnonthyroidalillnessonthyroidfunction [J] MedclinNothAm , 1985 , 6 9∶899 [4]ChopraIJ HepaticalterationsincirculatingthyroidhormonesandthyrotropininCirrhosis :evidenceforeuthyroidismdespiteSubnormalserumtriiodothyronine [J] JclinEndocrMetab , 1974, 39∶90 1 [5 ]李德泉 , 邝安 , 丁霆 , 等。肝硬化患者的甲状腺功能状态观察[J] 中华消化杂志 , 1983 , 3∶2 17 [][6 ]Bratusch -MarrainP , VierhapperH Grubech -LoebensteinB , etal Pituitary -thyroiddysfunctionSeverenonthyroidaldisease :low-T4-Syndrome[J] Endokrinologie , 1982 , 80∶2 0 7 [7]DavidF , GardnerMD , MichaelM , etal Effectoftriiodothyroninereplacementonthemetabolicandpituitaryresponsestostarvation[J] NEnglJMed , 1979, 30 0∶5 79 [8]UdayaM KabadiMD , BharturN etal SerumT3andreversT3levelsinhepaticcirrhosis :Relationtohepatocellularchangeandnormalizationonimprovementinliverdysfunction [J] AmJGastroenterology , 1983 , 78∶75 0 [9]温孚强 , 李卫东 , 孙远利 , 等。甲状腺素治疗肝硬化 2 7例疗效观察 [J] 中国实用内科杂志 , 1990 , 10∶47 -
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