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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 39 Issue 12
Dec.  2023
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Article Navigation >  Journal of Clinical Hepatology  > 2023  >  39(12): 2914-2919

Research advances in lean nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2023.12.024
  • 1.

    The First Clinical Medical College of Nanjing University of Chinese Medicine，Nanjing 210000，China

  • 2.

    Department of Endocrinology，The Affiliated Hospital of Nanjing University of Chinese Medicine，Nanjing 210000，China

Research funding:

Project of Administration of Traditional Chinese Medicine of Jiangsu Province of China (ZT202105)

More Information
  • Corresponding author: ZHOU Xiqiao， zhouxiqiao@njucm.edu.cn （ORCID： 0000-0003-3122-3904）
  • Received Date: 2023-03-29
  • Accepted Date: 2023-05-15
  • Published Date: 2023-12-12
    Abstract
  • Nonalcoholic fatty liver disease （NAFLD） is currently the main cause of chronic liver disease worldwide， and it can progress to hepatitis， liver fibrosis， liver cirrhosis， and even hepatocellular carcinoma. Although obesity plays a key role in the development of NAFLD， more and more studies have confirmed that NAFLD still exists in lean individuals， and lean NAFLD is associated with an increased risk of death and accelerated disease progression. Therefore， lean NAFLD also deserves careful evaluation and follow-up； however， we still know little about the pathophysiological mechanism of lean NAFLD. This article reviews the etiology， diagnosis， treatment， and prognosis of lean NAFLD.

     

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