A comparative analysis of the hemogram and myelogram of patients with liver cirrhosis and the advantages and disadvantages of splenectomy

Huimin LI; Yizhuo CHEN; Rui ZHAO; Xiao HUANG; Fei HUANG; Huanhuan LI

doi:10.3969/j.issn.1001-5256.2023.09.028

Volume 39 Issue 9

Sep. 2023

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Article Navigation > Journal of Clinical Hepatology > 2023 > 39(9): 2217-2224

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A comparative analysis of the hemogram and myelogram of patients with liver cirrhosis and the advantages and disadvantages of splenectomy

DOI: 10.3969/j.issn.1001-5256.2023.09.028

1.
Department of Obstetrics and Gynecology，The First Clinical Medical College of Xi’an Jiaotong University，Xi’an 710061，China
2.
The Second Clinical Medical College，Lanzhou University，Lanzhou 730000，China
3.
Department of Liver Diseases，Lanzhou University Second Hospital，Lanzhou 730000，China

Research funding:

The Second Hospital of Lanzhou University CUIYING Students Research And Cultivation Program (CYXZ2020－27)

More Information

Corresponding author: ZHAO Rui， ldeyzr@126.com （ORCID： 0000－0002－7986－0518）
Received Date: 2022-11-24
Accepted Date: 2022-12-29
Published Date: 2023-09-19

Abstract

Abstract

Compensated liver cirrhosis （CLC） and decompensated liver cirrhosis （DLC） are the two clinically distinct stages of liver cirrhosis. CLC often has atypical symptoms， while DLC has a variety of clinical manifestations， mainly hypersplenism， i.e.， splenomegaly with abnormal hemogram （reductions in white blood cell count， red blood cell count， and platelet count）. In China， the indications for splenectomy include secondary hypersplenism， space－occupying lesions in the spleen， and traumatic splenic rupture， among which secondary hypersplenism is frequently observed in DLC. However， after splenectomy， some patients have no improvement and experience a series of complications. It has long been assumed that hemogram changes in DLC patients are mainly associated with hypersplenism， while myelogram changes are not taken seriously and are often neglected. Identifying the cause of hemogram changes in such patients is the key to the selection of treatment methods. Therefore， by summarizing the association between the hemogram and myelogram of patients with DLC， this article points out the drawbacks of performing splenectomy at random， so as to provide correct knowledge and guidance for the treatment of patients with DLC and hypersplenism.
- Liver Cirrhosis,
- Hypersplenism,
- Splenectomy

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References(43)

References

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A comparative analysis of the hemogram and myelogram of patients with liver cirrhosis and the advantages and disadvantages of splenectomy

DOI: 10.3969/j.issn.1001-5256.2023.09.028

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A comparative analysis of the hemogram and myelogram of patients with liver cirrhosis and the advantages and disadvantages of splenectomy

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