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CN 22-1108/R
Volume 39 Issue 9
Sep.  2023
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Article Navigation >  Journal of Clinical Hepatology  > 2023  >  39(9): 2198-2204

Research progress of sarcopenia in patients with liver cirrhosis

DOI: 10.3969/j.issn.1001-5256.2023.09.025

  • Department of Gastroenterology，The 2nd Affiliated Hospital of Kunming Medical University，Kunming 650101，China

Research funding:

National Natural Science Foundation of China (82160106)

More Information
  • Corresponding author: YANG Jinhui， yangjinhuikyfey@163.com （ORCID： 0000－0002－4240－4025）
  • Received Date: 2022-12-11
  • Accepted Date: 2023-01-16
  • Published Date: 2023-09-19
    Abstract
  • Sarcopenia is a progressive and generalized muscle loss due to aging. With the deepening of research， it is found to be related to many chronic diseases. In patients with liver cirrhosis， owing to reduced protein intake， catabolism imbalance， insufficient self synthesis， and other reasons， the incidence of sarcopenia is extremely high， which negatively affects the treatment outcome and long－term survival， so it is an independent risk factor for poor prognosis in patients with liver cirrhosis. Therefore， it has important clinical value to manage sarcopenia in patients with liver cirrhosis. This review will explain the relationship between liver cirrhosis and sarcopenia from the aspects of definition， diagnosis， pathogenesis， clinical impact， and treatment.

     

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