中文｜English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 39 Issue 8
Aug.  2023
Turn off MathJax
Article Contents
Article Navigation >  Journal of Clinical Hepatology  > 2023  >  39(8): 1922-1925

Severe hyperbilirubinemia induced by hereditary spherocytosis: A case report

DOI: 10.3969/j.issn.1001-5256.2023.08.023

  • Digestive & Vascular Surgery Center/Department of Liver and Laparoscopic Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

More Information
  • Corresponding author: WEN Hao, dr.wenhao@163.com (ORDIC: 0000-0003-1016-1361)
  • Received Date: 2022-09-19
  • Accepted Date: 2023-02-09
  • Published Date: 2023-08-20
    Abstract
  • Hereditary spherocytosis is a type of hereditary hemolytic disease with human erythrocyte membrane defects and has the main symptoms of anemia, jaundice, and splenomegaly. Since its clinical symptoms are not typical, misdiagnosis or missed diagnosis is often observed. At present, there are rare cases with extremely high levels of total bilirubin and direct bilirubin in clinical practice, with few reports in China and globally. In this study, the patient had a total bilirubin level of 1 686.01 μmol/L and a direct bilirubin level of 1 166.6 μmol/L on admission. The patient was successfully discharged after surgical treatment and had good general conditions and high quality of life during follow-up. This article summarizes the experience in the diagnosis and surgical treatment of hereditary spherocytosis.

     

    • FullText(HTML)
  • loading
    • References(10)
  • [1]
    SHEN Y, LI MY, LIU XN, et al. ERC nursing care of a child with hereditary spherocytosis complicated with cholelithiasis: A case report[J]. Nurs Pract Res, 2021, 18(24): 3783-3786. DOI: 10.3969/j.issn.1672-9676.2021.24.039.

    沈艳, 李梦圆, 刘细妮, 等. 小儿遗传性球型红细胞增多症合并胆石症行ERC护理1例[J]. 护理实践与研究, 2021, 18(24): 3783-3786. DOI: 10.3969/j.issn.1672-9676.2021.24.039.
    [2]
    YANG L, SHI R, ZHANG YM. A case of extremely hyperbilirubinemia caused by hereditary spherocytosis combined with choledocholithiasis[J]. Chin J Hepatobiliary Surg, 2018, 24(12): 806, 811. DOI: 10.3760/cma.j.issn.1007-8118.2018.12.004.

    杨龙, 史瑞, 张雅敏. 遗传性球形红细胞增多症合并胆总管结石致极高胆红素血症一例[J]. 中华肝胆外科杂志, 2018, 24(12): 806, 811. DOI: 10.3760/cma.j.issn.1007-8118.2018.12.004.
    [3]
    LIN YB, SONG CY, LYU Y, et al. Clinical analysis of hereditary spherocytosis[J]. Int J Blood Transfus Hematol, 2020(2): 155-159. https://cdmd.cnki.com.cn/Article/CDMD-10403-1022636616.htm

    林云碧, 宋春艳, 吕瑜, 等. 遗传性球型红细胞增多症的临床分析[J]. 国际输血及血液学杂志, 2020(2): 155-159. https://cdmd.cnki.com.cn/Article/CDMD-10403-1022636616.htm
    [4]
    LIN QS, LI S, JIANG N, et al. PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation[J]. Redox Biol, 2019, 26: 101254. DOI: 10.1016/j.redox.2019.101254.
    [5]
    ZHANG D, WAN WQ. Hereditary polycythemia caused by mutation of ANK1 gene: A case report[J]. J Clin Pediatr, 2017, 35(9): 691-693. DOI: 10.3969/j.issn.1000-3606.2017.09.014.

    张丹, 万伍卿. ANK1基因突变致遗传性球型红细胞增多症1例报告[J]. 临床儿科杂志, 2017, 35(9): 691-693. DOI: 10.3969/j.issn.1000-3606.2017.09.014.
    [6]
    ZHOU D, CHEN YW, CAO HX, et al. Hyperbilirubinemia in a patient with hereditary spherocytosis and intrahepatic cholestasis[J]. J Pract Hepatol, 2015, 18(3): 310-311. DOI: 10.3969/j.issn.1672-5069.2015.02.028.

    周达, 陈源文, 曹海霞, 等. 遗传性球形红细胞增多症合并肝内胆汁淤积致严重高胆红血症1例[J]. 实用肝脏病杂志, 2015, 18(3): 310-311. DOI: 10.3969/j.issn.1672-5069.2015.02.028.
    [7]
    WEI NX, DING F, WANG SM, et al. Hereditary spherocytosis combined with malignant obstructive jaundice caused extreme hyperbiliru-binemia: A case report[J]. Chin J Hepatobiliary Surg, 2019, 25(10): 782-783. DOI: 10.3760/cma.j.issn.1007-8118.2019.10.017.

    魏宁心, 丁飞, 王石鸣, 等. 遗传性球形红细胞增多症合并恶性梗阻性黄疸致超高胆红素血症一例[J]. 中华肝胆外科杂志, 2019, 25(10): 782-783. DOI: 10.3760/cma.j.issn.1007-8118.2019.10.017.
    [8]
    TRIPODI SI, SHAMBERGER RC, HEENEY MM, et al. Clinical and laboratory outcomes following total or partial splenectomy in patients with hereditary spherocytosis[J]. Pediatr Hematol Oncol, 2019, 36(6): 382-389. DOI: 10.1080/08880018.2019.1637983.
    [9]
    WU ZQ. Acute renal failure[J]. Chin Pract J Rural Dr, 2022, 29(7): 14-15. DOI: 10.3969/j.issn.1672-7185.2022.07.007.

    吴钟琪. 急性肾衰竭[J]. 中国实用乡村医生杂志, 2022, 29(7): 14-15. DOI: 10.3969/j.issn.1672-7185.2022.07.007.
    [10]
    YE P, CHENG F. Role and mechanism of mitochondria in renal ischemia-reperfusion injury[J]. Med Recapitul, 2022, 28(4): 643-648. DOI: 10.3969/j.issn.1006-2084.2022.04.004.

    叶芃, 程帆. 线粒体在肾脏缺血再灌注损伤中的作用与机制[J]. 医学综述, 2022, 28(4): 643-648. DOI: 10.3969/j.issn.1006-2084.2022.04.004.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(3)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (377) PDF downloads(56) Cited by()
    Proportional views
    Related
        

    The first journal specializing in hepatobiliary and pancreatic diseases in China

    Supervisor：Ministry of Education of the People's Republic of China

    Sponsor：Jilin University

    Academic Support: Chinese Society of Hepatology，Chinese Medical Association

    Address: 461 Xinjiang Road, Changchun

    Submit：0431-88782044

    Peer review：0431-88783542

    Email：lcgdb@vip.163.com

    About Journal

    Submission Guideline

    Journal Online

    Hepatobiliary College

    Guidelines

    YesterdayIP[]YesterdayPV[]TodayIP[]TodayPV[]Online[]

    Website Design © 2020 Editorial Board of Journal of Clinical Hepatology 吉ICP备10000617号-1 Supported by: Beijing Renhe Information Technology Co. Ltd  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return