Advances in the risk factors, pathogenesis, and treatment of liver cirrhosis with osteoporosis

Qiu JIN; Jing YANG; Honglin MA; Qingqing LIU; Pingju LI; Shaoshan HU

doi:10.3969/j.issn.1001-5256.2023.04.028

Volume 39 Issue 4

Apr. 2023

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Article Navigation > Journal of Clinical Hepatology > 2023 > 39(4): 929-935

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Advances in the risk factors, pathogenesis, and treatment of liver cirrhosis with osteoporosis

DOI: 10.3969/j.issn.1001-5256.2023.04.028

Department of Gastroenterology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650000, China

Research funding:

Postgraduate Innovation Fund of Kunming Medical University in 2022 (2022S275);

Hospital Clinical Research Project of The Second Affiliated Hospital of Kunming Medical University (ynllT2021012)

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Corresponding author: YANG Jing, yangjing_dl@163.com (ORCID: 0000-0003-3305-8893)
Received Date: 2022-07-31
Accepted Date: 2022-09-20
Published Date: 2023-04-20

Abstract

Abstract

Osteoporosis is a common extrahepatic complication of liver cirrhosis, and it not only increases the economic burden of patients, but also brings adverse effects on their quality of life and prognosis. Recent studies have shown that sarcopenia, adiponectin, leptin, irisin, and inflammatory factors are involved in the development of osteoporosis in patients with liver cirrhosis, and commonly used anti-osteoporosis drugs include calcium supplement, vitamin D, and bisphosphonates. This article reviews the advances in the risk factors, pathogenesis, and treatment of liver cirrhosis with osteoporosis and points out that there are still controversies over the influence of some factors on osteoporosis, and further studies are needed to explore related pathogeneses and safe and effective treatment regimens.
- Liver Cirrhosis,
- Osteoporosis,
- Sarcopenia,
- Adiponectin,
- Irisin

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References(43)

References

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Advances in the risk factors, pathogenesis, and treatment of liver cirrhosis with osteoporosis

DOI: 10.3969/j.issn.1001-5256.2023.04.028

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Advances in the risk factors, pathogenesis, and treatment of liver cirrhosis with osteoporosis

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