[1] |
NGUYEN MH, WONG G, GANE E, et al. Hepatitis B virus: advances in prevention, diagnosis, and therapy[J]. Clin Microbiol Rev, 2020, 33(2): e00046-19. DOI: 10.1128/CMR.00046-19.
|
[2] |
WANG H, SHAN S, YOU H, et al. Effect of the change in antiviral therapy indication in increasing the treatment rate of chronic hepatitis B[J]. J Clin Hepatol, 2022, 38(6): 1269-1274. DOI: 10.3969/j.issn.1001-5256.2022.06.011.
王皓, 单珊, 尤红, 等. 抗病毒治疗适应症变化对提高慢性乙型肝炎治疗率的影响[J]. 临床肝胆病杂志, 2022, 38(6): 1269-1274. DOI: 10.3969/j.issn.1001-5256.2022.06.011.
|
[3] |
BUSTER EH, SCHALM SW, JANSSEN HL. Peginterferon for the treatment of chronic hepatitis B in the era of nucleos(t)ide analogues[J]. Best Pract Res Clin Gastroenterol, 2008, 22(6): 1093-1108. DOI: 10.1016/j.bpg.2008.11.007.
|
[4] |
YANG JM, CHEN LP, WANG YJ, et al. Entecavir add-on Peg-interferon therapy plays a positive role in reversing hepatic fibrosis in treatment-naïve chronic hepatitis B patients: a prospective and randomized controlled trial[J]. Chin Med J (Engl), 2020, 133(14): 1639-1648. DOI: 10.1097/CM9.0000000000000857.
|
[5] |
LIANG KH, HSU CW, CHANG ML, et al. Peginterferon is superior to nucleos(t)ide analogues for prevention of hepatocellular carcinoma in chronic hepatitis B[J]. J Infect Dis, 2016, 213(6): 966-974. DOI: 10.1093/infdis/jiv547.
|
[6] |
YUAN CH, LI CY, LI HL, et al. Efficacy of pegylated interferon α-2b in the treatment of patients with serum HBeAg positive chronic hepatitis B[J]. J Pract Hepatol, 2019, 22(3): 353-356. DOI: 10.3969/j.issn.1672-5069.2019.03.011.
袁春晖, 李春雨, 李红丽, 等. 国产聚乙二醇化干扰素α治疗HBeAg阳性慢性乙型肝炎患者疗效研究[J]. 实用肝脏病杂志, 2019, 22(3): 353-356. DOI: 10.3969/j.issn.1672-5069.2019.03.011.
|
[7] |
JI WJ, YAN XB. Clinical effect and safety of pegylated interferon-α-2a versus pegylated interferon-α-2b in treatment of chronic hepatitis B[J]. J Clin Hepatol, 2019, 35(2): 309-314. DOI: 10.3969/j.issn.1001-5256.2019.02.013.
嵇玮嘉, 颜学兵. 聚乙二醇干扰素α-2a与聚乙二醇干扰素α-2b治疗慢性乙型肝炎的效果及安全性比较[J]. 临床肝胆病杂志, 2019, 35(2): 309-314. DOI: 10.3969/j.issn.1001-5256.2019.02.013.
|
[8] |
LIN JX, YANG KL. Comparison of response to PEG-IFNα-2a or PEG-IFNα-2b in patients with chronic hepatitis B[J]. J Pract Hepatol, 2021, 24(1): 27-30. DOI: 10.3969/j.issn.1672-5069.2021.01.008.
林金祥, 杨可立. PEG-IFNα-2a与PEG-IFNα-2b治疗慢性乙型肝炎患者疗效研究[J]. 实用肝脏病杂志, 2021, 24(1): 27-30. DOI: 10.3969/j.issn.1672-5069.2021.01.008.
|
[9] |
NING Q, WU D, WANG GQ, et al. Roadmap to functional cure of chronic hepatitis B: An expert consensus[J]. J Viral Hepat, 2019, 26(10): 1146-1155. DOI: 10.1111/jvh.13126.
|
[10] |
SONG C, ZHU J, GE Z, et al. Spontaneous seroclearance of hepatitis B surface antigen and risk of hepatocellular carcinoma[J]. Clin Gastroenterol Hepatol, 2019, 17(6): 1204-1206. DOI: 10.1016/j.cgh.2018.08.019.
|
[11] |
LI GJ, YU YQ, CHEN SL, et al. Sequential combination therapy with pegylated interferon leads to loss of hepatitis B surface antigen and hepatitis B e antigen (HBeAg) seroconversion in HBeAg-positive chronic hepatitis B patients receiving long-term entecavir treatment[J]. Antimicrob Agents Chemother, 2015, 59(7): 4121-4128. DOI: 10.1128/AAC.00249-15.
|
[12] |
HUANG J, ZHANG K, CHEN W, et al. Switching to PegIFNα-2b leads to HBsAg loss in patients with low HBsAg levels and HBV DNA suppressed by NAs[J]. Sci Rep, 2017, 7(1): 13383. DOI: 10.1038/s41598-017-13747-9.
|
[13] |
WU FP, YANG Y, LI M, et al. Add-on pegylated interferon augments hepatitis B surface antigen clearance vs continuous nucleos(t)ide analog monotherapy in Chinese patients with chronic hepatitis B and hepatitis B surface antigen ≤ 1500 IU/mL: An observational study[J]. World J Gastroenterol, 2020, 26(13): 1525-1539. DOI: 10.3748/wjg.v26.i13.1525.
|
[14] |
REN P, LI H, HUANG Y, et al. A simple-to-use tool for predicting response to peginterferon in HBV DNA suppressed chronic hepatitis B patients in China[J]. Antiviral Res, 2021, 194: 105163. DOI: 10.1016/j.antiviral.2021.105163.
|
[15] |
European Association for the Study of the Liver. EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection[J]. J Hepatol, 2017, 67(2): 370-398. DOI: 10.1016/j.jhep.2017.03.021.
|
[16] |
MAK LY, SETO WK, FUNG J, et al. Use of HBsAg quantification in the natural history and treatment of chronic hepatitis B[J]. Hepatol Int, 2020, 14(1): 35-46. DOI: 10.1007/s12072-019-09998-5.
|
[17] |
ASSELAH T, LOUREIRO D, BOYER N, et al. Targets and future direct-acting antiviral approaches to achieve hepatitis B virus cure[J]. Lancet Gastroenterol Hepatol, 2019, 4(11): 883-892. DOI: 10.1016/S2468-1253(19)30190-6.
|
[18] |
YEH ML, HUANG JF, DAI CY, et al. Pharmacokinetics and pharmacodynamics of pegylated interferon for the treatment of hepatitis B[J]. Expert Opin Drug Metab Toxicol, 2019, 15(10): 779-785. DOI: 10.1080/17425255.2019.1678584.
|
[19] |
LEE IC, YANG SS, LEE CJ, et al. Incidence and predictors of HBsAg loss after peginterferon therapy in HBeAg-negative chronic hepatitis B: a multicenter, long-term follow-up study[J]. J Infect Dis, 2018, 218(7): 1075-1084. DOI: 10.1093/infdis/jiy272.
|
[20] |
WANG K, HUANG G, CHEN Y, et al. Hepatitis B surface antigen (HBsAg) kinetics in chronic hepatitis B patients during peginterferon treatment[J]. Med Sci Monit, 2020, 26: e921487. DOI: 10.12659/MSM.921487.
|
[21] |
LI MH, ZHANG L, QU XJ, et al. The predictive value of baseline HBsAg level and early response for HBsAg loss in patients with HBeAg-positive chronic hepatitis B during pegylated interferon alpha-2a treatment[J]. Biomed Environ Sci, 2017, 30(3): 177-184. DOI: 10.3967/bes2017.025.
|
[22] |
ZHANG S, WANG YH, SUN J, et al. Effect of antiviral therapy combined with interferon on negative conversion rate of surface antigen among patients of chronic hepatitis B treated with nucleos(t)ide analogues[J/CD]. Chin J Exp Clin Infect Dis (Electronic Edition), 2019, 13(4): 273-280.
张珊, 王艺璇, 孙静, 等. 干扰素联合抗病毒治疗对提高核苷(酸)类药物经治慢性乙型肝炎患者表面抗原阴转率的影响[J/CD]. 中华实验和临床感染病杂志(电子版), 2019, 13(4): 273-280.
|
[23] |
Chinese Society of Infectious Diseases, Chinese Medical Association; Chinese Society of Hepatology, Chinese Medical Association. Guidelines for prevention and treatment of chronic hepatitis B (version 2019)[J]. J Clin Hepatol, 2019, 35(12): 2648-2669. DOI: 10.3969/j.issn.1001-5256.2019.12.007.
中华医学会感染病学分会, 中华医学会肝病学分会. 慢性乙型肝炎防治指南(2019年版)[J]. 临床肝胆病杂志, 2019, 35(12): 2648-2669. DOI: 10.3969/j.issn.1001-5256.2019.12.007.
|
[24] |
CHOI H, SONNEVELD MJ, FARAG MS, et al. Effects of on-treatment ALT flares on serum HBsAg and HBV RNA in patients with chronic HBV infection[J]. J Viral Hepat, 2021, 28(12): 1729-1737. DOI: 10.1111/jvh.13613.
|
[25] |
MATSUMOTO A, NISHIGUCHI S, ENOMOTO H, et al. Combinational use of hepatitis B viral antigens predicts responses to nucleos(t)ide analogue/peg-interferon sequential therapy[J]. J Gastroenterol, 2018, 53(2): 247-257. DOI: 10.1007/s00535-017-1360-z.
|
[26] |
BOGLIONE L, CARITI G, DI PERRI G, et al. Sequential therapy with entecavir and pegylated interferon in a cohort of young patients affected by chronic hepatitis B[J]. J Med Virol, 2016, 88(11): 1953-1959. DOI: 10.1002/jmv.24534.
|
[27] |
FARAG MS, van CAMPENHOUT M, PFEFFERKORN M, et al. Hepatitis B virus RNA as early predictor for response to pegylated interferon alpha in HBeAg-negative chronic hepatitis B[J]. Clin Infect Dis, 2021, 72(2): 202-211. DOI: 10.1093/cid/ciaa013.
|
[28] |
JINATO T, CHUAYPEN N, POOMIPAK W, et al. Original research: analysis of hepatic microRNA alterations in response to hepatitis B virus infection and pegylated interferon alpha-2a treatment[J]. Exp Biol Med (Maywood), 2016, 241(16): 1803-1810. DOI: 10.1177/1535370216647184.
|
[29] |
YANG Y, LIU M, DENG Y, et al. Pretreatment microRNA levels can predict HBsAg clearance in CHB patients treated with pegylated interferon α-2a[J]. Virol J, 2018, 15(1): 73. DOI: 10.1186/s12985-018-0982-y.
|
[30] |
SONNEVELD MJ, ARENDS P, BOONSTRA A, et al. Serum levels of interferon-gamma-inducible protein 10 and response to peginterferon therapy in HBeAg-positive chronic hepatitis B[J]. J Hepatol, 2013, 58(5): 898-903. DOI: 10.1016/j.jhep.2013.01.029.
|
[31] |
LAMPERTICO P, VIGANÒ M, CHERONI C, et al. IL28B polymorphisms predict interferon-related hepatitis B surface antigen seroclearance in genotype D hepatitis B e antigen-negative patients with chronic hepatitis B[J]. Hepatology, 2013, 57(3): 890-896. DOI: 10.1002/hep.25749.
|