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CN 22-1108/R
Volume 38 Issue 11
Nov.  2022
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Article Navigation >  Journal of Clinical Hepatology  > 2022  >  38(11): 2616-2620

Current research status and prospect of circulating tumor DNA in hepatocellular carcinoma

DOI: 10.3969/j.issn.1001-5256.2022.11.036

  • Department of Hepatobiliary Surgery, Affiliated Hospital of Hebei University, Baoding, Hebei 071000, China

Research funding:

Natural Science Foundation of Hebei Province (18277790D)

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  • Corresponding author: CHENG Shujie, chengshuj@126.com (ORCID: 0000-0003-2646-3938)
  • Received Date: 2022-04-01
  • Accepted Date: 2022-06-30
  • Published Date: 2022-11-20
    Abstract
  • Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world, with the features of insidious onset, low surgical resection rate, and frequent early metastasis and recurrence. With the development of new molecular biology technology in recent years, a liquid biopsy technology, circulating tumor DNA (ctDNA) detection, has achieved encouraging results. This article reviews the current research status and future prospects of ctDNA as a key component of liquid biopsy in patients with HCC, in order to provide new ideas for the clinical treatment of HCC.

     

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