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ISSN 2097-3497 (Online)
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Volume 38 Issue 5
May  2022
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Article Navigation >  Journal of Clinical Hepatology  > 2022  >  38(5): 1188-1191

Advances in the clinical research on liver transplantation in treatment of acute-on-chronic liver failure

DOI: 10.3969/j.issn.1001-5256.2022.05.045
  • 1.

    Department of Liver Transplantation, Tianjin First Central Hospital, Tianjin 300110, China

  • 2.

    The First Central College of Tianjin Medical University, Tianjin 300110, China

Research funding:

Nation Natural Science Foundation of China (General Program) (82072219);

Natural Science Foundation of Tianjin (17JCQNJC12800)

More Information
  • Corresponding author: LI Jiang, lijiang_009@163.com(ORCID: 0000-0002-2368-9942)
  • Received Date: 2021-09-14
  • Accepted Date: 2021-10-18
  • Published Date: 2022-05-20
    Abstract
  • Acute-on-chronic liver failure (ACLF) is a disease of rapid deterioration of liver function caused by the acute exacerbation of chronic liver diseases, and it is often associated with multiple organ failure and has a poorer prognosis than common liver cirrhosis. Many studies suggest that timely liver transplantation can significantly improve the survival rate of patients with ACLF; however, there are currently no reliable guidelines that point out the indications for liver transplantation in patients with ACLF. This article summarizes recent studies and discusses the indication, timing, and prognosis of liver transplantation in ALCF patients.

     

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    • References(38)
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