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CN 22-1108/R
Volume 38 Issue 4
Apr.  2022
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Expert consensus on clinical application of artificial liver and blood purification (2022 edition)

DOI: 10.3969/j.issn.1001-5256.2022.04.007
  • Received Date: 2022-02-14
  • Accepted Date: 2022-03-16
  • Published Date: 2022-04-20
  • HAN Tao, hantaomd@126.com (ORCID: 0000-0003-4216-6968); CHEN Yu, chybeyond1071@ccmu.edu.cn (ORCID: 0000-0001-7612-3240); DUAN Zhongping, duan@ccmu.edu.cn (ORCID: 0000-0002-8455-0426)
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  • [1]
    Liver Failure and Artificial Liver Group, Chinese Society of Infectious Diseases, Chinese Medical Association; Severe Liver Disease and Artificial Liver Group, Chinese Society of Hepatology, Chinese Medical Association. Guideline for diagnosis and treatment of liver failure(2018)[J]. J Clin Hepatol, 2019, 35(1): 38-44. DOI: 10.3969/j.issn.1001-5256.2019.01.007.

    中华医学会感染病学分会肝衰竭与人工肝学组, 中华医学会肝病学分会重型肝病与人工肝学组. 肝衰竭诊治指南(2018年版)[J]. 临床肝胆病杂志, 2019, 35(1): 38-44. DOI: 10.3969/j.issn.1001-5256.2019.01.007.
    [2]
    Liver Failure and Artificial Liver Group, Chinese Society of Infectious Diseases, Chinese Medical Association. Guideline for non-bioartificial liver support systems in treatment of liver failure: 2016 update[J]. Chin J Clin Infect Dis, 2016, 9(2): 97-103. DOI: 10.3760/cma.j.issn.1674-2397.2016.02.001.

    中华医学会感染病学分会肝衰竭与人工肝学组. 非生物型人工肝治疗肝衰竭指南(2016年版)[J]. 中华临床感染病杂志, 2016, 9(2): 97-103. DOI: 10.3760/cma.j.issn.1674-2397.2016.02.001.
    [3]
    European Association for the Study of the Liver. EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure[J]. J Hepatol, 2017, 66(5): 1047-1081. DOI: 10.1016/j.jhep.2016.12.003.
    [4]
    GUO X, WU F, GUO W, et al. Comparison of plasma exchange, double plasma molecular adsorption system, and their combination in treating acute-on-chronic liver failure[J]. J Int Med Res, 2020, 48(6): 300060520932053. DOI: 10.1177/0300060520932053.
    [5]
    XU MM, KONG M, CAO YY, et al. A new perspective on acute-on-chronic liver failure based on clinical outcome of dynamic classification criteria[J]. Chin J Hepatol, 2020, 28(4): 319-325. DOI: 10.3760/cma.j.cn501113-0309-00099.

    徐曼曼, 孔明, 曹影影, 等. 慢加急性肝衰竭分型新视点: 基于临床转归的动态分型新标准[J]. 中华肝脏病杂志, 2020, 28(4): 319-325. DOI: 10.3760/cma.j.cn501113-0309-00099.
    [6]
    XU MM, KONG M, YU PF, et al. Clinical course and outcome patterns of acute-on-chronic liver failure: A multicenter retrospective cohort study[J]. J Clin Transl Hepatol, 2021, 9(5): 626-634. DOI: 10.14218/JCTH.2020.00179.
    [7]
    LI J, LIANG X, YOU S, et al. Development and validation of a new prognostic score for hepatitis B virus-related acute-on-chronic liver failure[J]. J Hepatol, 2021, 75(5): 1104-1115. DOI: 10.1016/j.jhep.2021.05.026.
    [8]
    Vascular Access Working Group of Blood Purification Center Branch of Chinese Hospital Association. Expert consensus on vascular access for hemodialysis in China (2nd edition)[J]. Chin J Blood Purificat, 2019, 18(6): 365-381. DOI: 10.3969/j.issn.1671-4091.2019.06.001.

    中国医院协会血液净化中心分会血管通路工作组. 中国血液透析用血管通路专家共识(第2版)[J]. 中国血液净化, 2019, 18(6): 365-381. DOI: 10.3969/j.issn.1671-4091.2019.06.001.
    [9]
    CHEN F, XU Y, ZHOU SQ, et al. Application comparison between internal jugular vein catheterization and femoral vein catheterization in artificial liver support system in patients with liver failure[J]. Chin J Integr Tradit West Med Intensive Crit Care, 2019, 26(6): 688-690. DOI: 10.3969/j.issn.1008-9691.2019.06.013.

    陈芳, 许艳, 周少群, 等. 颈内静脉置管与股静脉置管在肝衰竭患者人工肝治疗中的应用比较[J]. 中国中西医结合急救杂志, 2019, 26(6): 688-690. DOI: 10.3969/j.issn.1008-9691.2019.06.013.
    [10]
    National Technical Committee on Standardization of Quality Management and Quality Assurance. Understanding and implementation of national standard of quality management system (2016 edition)[M]. Beijing: Standards Press of China, 2017.

    全国质量管理和质量保证标准化技术委员会. 2016版质量管理体系国家标准理解与实施[M]. 北京: 中国标准出版社, 2017.
    [11]
    LI S, ZHOU L, LIU J, et al. Clinical observation of plasma exchange replacement of partial plasma with hydroxyethyl starch in the treatment of patients with liver failure[J]. Chin J Gastroenterol Hepatol, 2019, 28(7): 735-739. DOI: 10.3969/j.issn.1006-5709.2019.07.004.

    李爽, 周莉, 刘静, 等. 血浆置换应用羟乙基淀粉替代部分血浆治疗肝衰竭的临床观察[J]. 胃肠病学和肝病学杂志, 2019, 28(7): 735-739. DOI: 10.3969/j.issn.1006-5709.2019.07.004.
    [12]
    LI S, LIU J, CHEN Y. Non-bioartificial liver in liver failure: Clinical application and research advances[J]. J Clin Hepatol, 2019, 35(9): 1909-1915. DOI: 10.3969/j.issn.1001-5256.2019.09.004.

    李爽, 刘静, 陈煜. 非生物型人工肝在肝衰竭中的临床应用及进展[J]. 临床肝胆病杂志, 2019, 35(9): 1909-1915. DOI: 10.3969/j.issn.1001-5256.2019.09.004.
    [13]
    LI S, CHEN Y. Coping with shortage of plasma-The new therapeutic pattern of non-bioartificial liver[J]. J Clin Hepatol, 2017, 33(9): 1687-1692. DOI: 10.3969/j.issn.1001-5256.2017.09.012.

    李爽, 陈煜. 血浆紧缺情况下非生物型人工肝治疗新模式的探讨[J]. 临床肝胆病杂志, 2017, 33(9): 1687-1692. DOI: 10.3969/j.issn.1001-5256.2017.09.012.
    [14]
    DUAN ZP, CHEN Y. Clinical application of artificial livers[J]. Chin J Hepatol, 2010, 18(11): 808-810. DOI: 10.3760/cma.j.issn.1007-3418.2010.11.004.

    段钟平, 陈煜. 人工肝的临床应用[J]. 中华肝脏病杂志, 2010, 18(11): 808-810. DOI: 10.3760/cma.j.issn.1007-3418.2010.11.004.
    [15]
    DUAN ZP, LIU Q. Artificial liver treatment[M]. Beijing: China Medical Science Press, 2002.

    段钟平, 刘青. 人工肝脏治疗学[M]. 北京: 中国医药科技出版社, 2002.
    [16]
    XU JZ, DUAN ZP. Practical handbook of artificial liver and blood purification[M]. Beijing: China Medical Science Press, 2005: 56-58.

    许家璋, 段钟平. 实用人工肝及血液净化操作手册[M]. 北京: 中国医药科技出版社, 2005: 56-58.
    [17]
    General Office of National Health Commission. Blood Purification Standard Operating Procedure (2021 Edition)[S/OL]. [2021-11-09]. http://www.nhc.gov.cn/yzygj/s7659/202111/6e25b8260b214c55886d6f0512c1e53f.shtml.

    国家卫生健康委办公厅. 血液净化标准操作规程(2021版)[S/OL]. [2021-11-09]. http://www.nhc.gov.cn/yzygj/s7659/202111/6e25b8260b214c55886d6f0512c1e53f.shtml.
    [18]
    LI RH, FU L, HUANG Y, et al. Clinical research of double plasma molecular absorption system in treatment of liver failure[J]. Chin J Mod Med, 2018, 28(1): 78-82. DOI: 10.3969/j.issn.1005-8982.2018.01.015.

    李荣华, 傅蕾, 黄燕, 等. 双重血浆分子吸附治疗肝衰竭的临床研究[J]. 中国现代医学杂志, 2018, 28(1): 78-82. DOI: 10.3969/j.issn.1005-8982.2018.01.015.
    [19]
    QIN H, WEI L. Clinical effect of double plasma absorption combined with plasma exchange therapy in acute-on-chronic liver failure[J]. Clin Focus, 2019, 34(7): 633-636. DOI: 10.3969/j.issn.1004-583X.2019.07.013.

    秦华, 魏丽. 双重血浆分子吸附联合血浆置换治疗慢加急性肝衰竭的疗效分析[J]. 临床荟萃, 2019, 34(7): 633-636. DOI: 10.3969/j.issn.1004-583X.2019.07.013.
    [20]
    YAO J, LI S, ZHOU L, et al. Therapeutic effect of double plasma molecular adsorption system and sequential half-dose plasma exchange in patients with HBV-related acute-on- chronic liver failure[J]. J Clin Apher, 2019, 34(4): 392-398. DOI: 10.1002/jca.21690.
    [21]
    MACDONALD AJ, KARVELLAS CJ. Emerging role of extracorporeal support in acute and acute-on-chronic liver failure: Recent developments[J]. Semin Respir Crit Care Med, 2018, 39(5): 625-634. DOI: 10.1055/s-0038-1675334.
    [22]
    LARSEN FS. Artificial liver support in acute and acute-on-chronic liver failure[J]. Curr Opin Crit Care, 2019, 25(2): 187-191. DOI: 10.1097/MCC.0000000000000584.
    [23]
    YANG XS, ZHOU L, LI L, et al. Influence of duration of plasma diafiltration on therapeutic outcome of liver failure[J]. J Clin Hepatol, 2018, 34(5): 1052-1054. DOI: 10.3969/j.issn.1001-5256.2018.05.025.

    杨仙珊, 周莉, 李璐, 等. 血浆透析滤过治疗时间对肝衰竭治疗效果的影响[J]. 临床肝胆病杂志, 2018, 34(5): 1052-1054. DOI: 10.3969/j.issn.1001-5256.2018.05.025.
    [24]
    WANG ZG. Blood purification[M]. 4th ed. Beijing: Beijing Science and Technology Press, 2016.

    王质刚. 血液净化学[M]. 4版. 北京: 北京科学技术出版社, 2016.
    [25]
    LIU DW, YANG RL, CHEN XK. Critical care blood purification[M]. Beijing: People's Medical Publishing House, 2017.

    刘大为, 杨荣利, 陈秀凯. 重症血液净化[M]. 北京: 人民卫生出版社, 2017.
    [26]
    LA MANNA G, DONATI G. Coupled plasma filtration adsorption: A multipurpose extracorporeal detoxification therapy[J]. Blood Purif, 2018, 46(3): 228-238. DOI: 10.1159/000490234.
    [27]
    GARBERO E, LIVIGNI S, FERRARI F, et al. High dose coupled plasma filtration and adsorption in septic shock patients. Results of the COMPACT-2: A multicentre, adaptive, randomised clinical trial[J]. Intensive Care Med, 2021, 47(11): 1303-1311. DOI: 10.1007/s00134-021-06501-3.
    [28]
    PEZZI M, RENDA S, GIGLIO AM, et al. The use of coupled plasma filtration adsorption in traumatic rhabdomyolysis[J]. Case Rep Crit Care, 2017, 2017: 5764961. DOI: 10.1155/2017/5764961.
    [29]
    MARIANO F, HOLLO' Z, DEPETRIS N, et al. Coupled-plasma filtration and adsorption for severe burn patients with septic shock and acute kidney injury treated with renal replacement therapy[J]. Burns, 2020, 46(1): 190-198. DOI: 10.1016/j.burns.2019.05.017.
    [30]
    HIRANO R, NAMAZUDA K, HIRATA N. Double filtration plasmapheresis: Review of current clinical applications[J]. Ther Apher Dial, 2021, 25(2): 145-151. DOI: 10.1111/1744-9987.13548.
    [31]
    CHEN YH, GONG DH, LIU ZZ, et al. A preliminary study of double filtration plasmapheresis in ANCA associated vasculitis with severe renal involvement[J]. Chin J Nephrol Dialysis Transplantation, 2012, 21(1): 8-13. DOI: 10.3969/j.issn.1006-298X.2012.01.002.

    陈樱花, 龚德华, 刘正钊, 等. 双重血浆置换治疗抗中性粒细胞胞质抗体相关血管炎严重肾损害的临床疗效[J]. 肾脏病与透析肾移植杂志, 2012, 21(1): 8-13. DOI: 10.3969/j.issn.1006-298X.2012.01.002.
    [32]
    YANG X, SUN XF. Double filtration plasma exchange therapy[J]. J Inter Intens Med, 2006, 12(1): 39, 43. DOI: 10.3969/j.issn.1007-1024.2006.01.016.

    杨晓, 孙希锋. 双重滤过血浆置换疗法[J]. 内科急危重症杂志, 2006, 12(1): 39, 43. DOI: 10.3969/j.issn.1007-1024.2006.01.016.
    [33]
    WEI GL, YE H, SHI CF, et al. Efficacy of double filtration plasmapheresis in patients with refractory hyperlipidemia[J]. Chin J Nephrol Dialysis Transplantation, 2021, 30(4): 332-336. DOI: 10.3969/j.issn.1006-298X.2021.04.006.

    魏桂玲, 叶红, 石彩凤, 等. 双重血浆置换在难治性高脂血症患者的临床应用[J]. 肾脏病与透析肾移植杂志, 2021, 30(4): 332-336. DOI: 10.3969/j.issn.1006-298X.2021.04.006.
    [34]
    ALBAYRAK M, Y1LD1Z A, ATEŞN, et al. The efficacy of double filtration plasmapheresis in the treatment of homozygous familial hypercholesterolemia: A single-center experience[J]. Transfus Apher Sci, 2019, 58(1): 61-64. DOI: 10.1016/j.transci.2018.11.007.
    [35]
    LIU HT, ZHANG LX, LIU Q, et al. Comparative study of dual plasma filtration plasmapheresis and plasma exchange in the preconditioning of ABO incompatible renal transplantation[J]. Chin J Organ Transplant, 2020, 41(10): 603-607. DOI: 10.3760/cma.j.cn421203-20200727-00253.

    刘洪涛, 张乐希, 刘潜, 等. 双重血浆滤过与血浆置换在ABO血型不相容肾移植术前预处理中的对比研究[J]. 中华器官移植杂志, 2020, 41(10): 603-607. DOI: 10.3760/cma.j.cn421203-20200727-00253.
    [36]
    IWAMI D, MIURA M, CHIBA Y, et al. Optimal settings for double filtration plasmapheresis with targeted removal rate of preexisting antibody in antibody-incompatible kidney transplant[J]. Transplant Proc, 2018, 50(10): 3478-3482. DOI: 10.1016/j.transproceed.2018.05.023.
    [37]
    MITZNER SR, STANGE J, KLAMMT S, et al. Albumin dialysis MARS: Knowledge from 10 years of clinical investigation[J]. ASAIO J, 2009, 55(5): 498-502. DOI: 10.1097/MAT.0b013e3181b37d86.
    [38]
    MULLOY B, HOGWOOD J, GRAY E, et al. Pharmacology of heparin and related drugs[J]. Pharmacol Rev, 2016, 68(1): 76-141. DOI: 10.1124/pr.115.011247.
    [39]
    SHUNKWILER SM, PHAM HP, WOOL G, et al. The management of anticoagulation in patients undergoing therapeutic plasma exchange: A concise review[J]. J Clin Apher, 2018, 33(3): 371-379. DOI: 10.1002/jca.21592.
    [40]
    GRAY E, HOGWOOD J, MULLOY B. The anticoagulant and antithrombotic mechanisms of heparin[J]. Handb Exp Pharmacol, 2012, 207: 43-61. DOI: 10.1007/978-3-642-23056-1_3.
    [41]
    KONG M, LI S, GENG H, et al. Influencing factors of heparin anticoagulant effect in the treatment of double plasma molecular adsorption system[J]. J Capit Med Univ, 2021, 42(4): 647-652. DOI: 10.3969/j.issn.1006-7795.2021.04.022.

    孔明, 李爽, 耿华, 等. 双重血浆分子吸附系统治疗过程中肝素抗凝效果的影响因素研究[J]. 首都医科大学学报, 2021, 42(4): 647-652. DOI: 10.3969/j.issn.1006-7795.2021.04.022.
    [42]
    MA Y, CHEN F, XU Y, et al. Safety and efficacy of regional citrate anticoagulation during plasma adsorption plus plasma exchange therapy for patients with acute-on-chronic liver failure: A pilot study[J]. Blood Purif, 2019, 48(3): 223-232. DOI: 10.1159/000500408.
    [43]
    MA Y, CHEN F, LIU C, et al. A novel predictive score for citrate accumulation among patients receiving artificial liver support system therapy with regional citrate anticoagulation[J]. Sci Rep, 2020, 10(1): 12861. DOI: 10.1038/s41598-020-69902-2.
    [44]
    XU Y, CHEN F, WANG Y, et al. Nursing care of patients with liver failure undergoing plasma adsorption plus sequential plasma exchange artificial liver model therapy combined with regional citrate anticoagulation[J]. Chin J Integr Tradit West Med Intensive Crit Care, 2019, 26(6): 685-687. DOI: 10.3969/j.issn.1008-9691.2019.06.012.

    许艳, 陈芳, 王颖, 等. 血浆吸附序贯血浆置换人工肝模式治疗肝衰竭应用局部拘椽酸抗凝的护理[J]. 中国中西医结合急救杂志, 2019, 26(6): 685-687. DOI: 10.3969/j.issn.1008-9691.2019.06.012.
    [45]
    WU CB, ZHOU MX, MENG Y, et al. Application and research progress of non-bioartificial liver[J]. BME & Clin Med, 2021, 25(5): 634-638. DOI: 10.13339/j.cnki.sglc.20210820.009.

    吴春波, 周明雪, 孟彦, 等. 非生物型人工肝的应用及研究进展[J]. 生物医学工程与临床, 2021, 25(5): 634-638. DOI: 10.13339/j.cnki.sglc.20210820.009.
    [46]
    LIU L, HAN T. Advances in the application of non-bioartificial liver in treatment of non-liver failure diseases[J]. J Clin Hepatol, 2020, 36(9): 2115-2118. DOI: 10.3969/j.issn.1001-5256.2020.09.047.

    刘磊, 韩涛. 非生物型人工肝在非肝衰竭疾病治疗中的应用进展[J]. 临床肝胆病杂志, 2020, 36(9): 2115-2118. DOI: 10.3969/j.issn.1001-5256.2020.09.047.
    [47]
    ZHANG F, QIU YM, HUANG JH, et al. Study on the application of improved nursing process in the treatment of severe hepatitis artificial liver[J]. Chin Modern Med, 2019, 25(20): 181-183. DOI: 10.3969/j.issn.1009-4393.2019.20.079.
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