Research advances in the protective effect of sulforaphane against liver injury and related mechanisms

Xinyu MA; Tingting DUAN; Jingya XU; Jiahe ZHAO; Chunlei ZHANG; Baolong LI

doi:10.3969/j.issn.1001-5256.2022.01.036

Volume 38 Issue 1

Jan. 2022

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Article Navigation > Journal of Clinical Hepatology > 2022 > 38(1): 206-209

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Research advances in the protective effect of sulforaphane against liver injury and related mechanisms

DOI: 10.3969/j.issn.1001-5256.2022.01.036

1.
Center for Safety Evaluation of Drugs, Heilongjiang University of Chinese Medicine, Harbin 150040, China
2.
Jiamusi College, Heilongjiang University of Chinese Medicine, Jiamusi, Heilongjiang 154000, China

Research funding:

General Project of National Natural Science Foundation of China (81573135);

Science and Technology Research Project of Heilongjiang Provincial Department of Education (12541763)

Received Date: 2021-06-19
Accepted Date: 2021-07-21
Published Date: 2022-01-20

Abstract

Abstract

Sulforaphane is a phytochemical with a variety of biological activities that exists widely in Cruciferae plants. This article summarizes the recent experimental studies of sulforaphane in the treatment of various types of liver injury in China and globally and reviews the role and mechanism of sulforaphane in protecting against liver injury. Based on the experimental animal models of liver injury, this article summarizes the therapeutic effect of sulforaphane on the models of chemical liver injury, drug-induced liver injury, alcoholic liver injury, immunological liver injury, and ischemia/reperfusion liver injury and analyzes the mechanism of action of sulforaphane in improving experimental liver injury, so as to provide a reference for in-depth research on sulforaphane in protecting against liver injury.
- Sulforaphane,
- Liver Injury,
- Pathologic Processes

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References(33)

References

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Research advances in the protective effect of sulforaphane against liver injury and related mechanisms

DOI: 10.3969/j.issn.1001-5256.2022.01.036

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Research advances in the protective effect of sulforaphane against liver injury and related mechanisms

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