Mechanism of autophagy in the development and progression of autoimmune hepatitis

Peiwei YANG; Guangwei LIU; Wenxia ZHAO

doi:10.3969/j.issn.1001-5256.2021.11.044

Volume 37 Issue 11

Nov. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(11): 2689-2691

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Mechanism of autophagy in the development and progression of autoimmune hepatitis

DOI: 10.3969/j.issn.1001-5256.2021.11.044

Department of Hepatology and Spleen-Stomach, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China

Research funding:

National Natural Science Foundation of China (82003994);

Henan Province Traditional Chinese Medicine Research Project (2019JDZX2034)

Received Date: 2021-03-01
Accepted Date: 2021-03-26
Published Date: 2021-11-20

Abstract

Abstract

Autophagy is a process of self-defense and self-repair of cells and tissues and plays an important role in regulating the body's immune inflammatory response and maintaining the homeostasis of liver cells. This article summarizes the mechanism of autophagy in the development and progression of autoimmune hepatitis (AIH) from the aspects of the role of autophagy in regulating immune inflammatory response, regulating immune signal transduction, and preventing overactivated innate immune response. It is believed that autophagy may reveal the mechanism of AIH and provide new ideas and methods for the research on AIH.
- Hepatitis, Autoimmune,
- Autophagy,
- Immunity, Innate

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References(36)

References

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Mechanism of autophagy in the development and progression of autoimmune hepatitis

DOI: 10.3969/j.issn.1001-5256.2021.11.044

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Mechanism of autophagy in the development and progression of autoimmune hepatitis

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