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ISSN 2097-3497 (Online)
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Volume 37 Issue 11
Nov.  2021
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Article Navigation >  Journal of Clinical Hepatology  > 2021  >  37(11): 2680-2683

Role of angiopoietin-like proteins in the development of nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2021.11.042
  • 1.

    Graduate School of Shanxi Medical University, Taiyuan 030001, China

  • 2.

    Department of Gastroenterology, The First Hospital of Shanxi Medical University, Taiyuan 030001, China

Research funding:

Scientific and Technological Achievements Transformation Guidance Special of Shanxi Province, China (201904D131030)

  • Received Date: 2021-03-14
  • Accepted Date: 2021-04-19
  • Published Date: 2021-11-20
    Abstract
  • Angiopoietin-like proteins (ANGPTLs) are a family of secretory glycoproteins recently found to be constitutionally homologous with angiogenin and play a role in the regulation of angiogenesis. In recent years, more and more studies have shown that ANGPTLs play an important role in glucose and lipid metabolism, inflammation, and tumor. As we all know, nonalcoholic fatty liver disease and its disease spectrum are closely associated with metabolism, inflammation, and tumor. This article reviews the role of ANGPTLs in various diseases associated with nonalcoholic fatty liver disease, in order to provide new ideas for the prevention and treatment of nonalcoholic fatty liver disease in clinical practice.

     

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