Effect of diet-gut microbiota axis on nonalcoholic fatty liver disease

Shenglan ZENG; Rongzhen ZHANG; Na WANG; Tingshuai WANG; Liting TAN; Dewen MAO

doi:10.3969/j.issn.1001-5256.2021.11.041

Volume 37 Issue 11

Nov. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(11): 2676-2679

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Effect of diet-gut microbiota axis on nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2021.11.041

1.
The First Clinical Medical College of Guangxi University of Chinese Medicine, Nanning 530023, China
2.
Division I of Liver Disease, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530023, China

Research funding:

National Natural Science Foundation of China (81960841);

National Natural Science Foundation of China (81774236);

National Natural Science Foundation of China (82060848);

National Natural Science Foundation of Guangxi Province (2020JJA140273);

Guangxi Science and Technology Program Project (GK AD17129001);

State Administration of Traditional Chinese Medicine Key Laboratory of Detoxicating and Stasis-resolving Therapy for Severe Chronic Hepatitis

Received Date: 2021-03-12
Accepted Date: 2021-03-31
Published Date: 2021-11-20

Abstract

Abstract

The incidence rate of nonalcoholic fatty liver disease (NAFLD) is increasing. Diet is considered one of the main driving forces regulating the composition of intestinal microbiota, and the intestine and the liver are closely linked through the portal vein, so changes in gut microbiota may affect liver function and promote inflammation, insulin resistance, and steatosis, thereby causing NAFLD. This article elaborates on the relationship between diet, gut microbiota, and the liver and the research advances in how this axis promotes the progression of NAFLD, as well as the change in potential mechanism due to intestinal dysbacteriosis and related treatment methods.
- Non-alcoholic Fatty Liver Disease,
- Gastrointestinal Microbiome,
- Healthy Diet

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References

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Effect of diet-gut microbiota axis on nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2021.11.041

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Effect of diet-gut microbiota axis on nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2021.11.041

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