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Volume 37 Issue 11
Nov.  2021
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Article Navigation >  Journal of Clinical Hepatology  > 2021  >  37(11): 2539-2540

Patients with chronic hepatitis B virus infection in the indeterminate phase may benefit from antiviral therapy

DOI: 10.3969/j.issn.1001-5256.2021.11.007

  • Department of Infectious Diseases, Peking University First Hospital, Beijing 100034, China

  • Received Date: 2021-09-13
  • Accepted Date: 2021-09-13
  • Published Date: 2021-11-20
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    • References(7)
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    Chinese Society of Infectious Diseases, Chinese Medical Association, Chinese Society of Hepatology, Chinese Medical Association. Guidelines for the prevention and treatment of chronic hepatitis B (version 2019)[J]. J Clin Hepatol, 2019, 35(12): 2648-2669. DOI: 10.3969/j.issn.1001-5256.2019.12.007.

    中华医学会感染病学分会, 中华医学会肝病学分会. 慢性乙型肝炎防治指南(2019年版)[J]. 临床肝胆病杂志, 2019, 35(12): 2648-2669. DOI: 10.3969/j.issn.1001-5256.2019.12.007.
    [2]
    TERRAULT NA, LOK ASF, MCMAHON BJ, et al. Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance[J]. Hepatology, 2018, 67 (4): 1560-1599. DOI: 10.1002/hep.29800.
    [3]
    HUANG DQ, LI X, LE MH, et al. Natural history and hepatocellular carcinoma risk in untreated chronic hepatitis B patients with indeterminate phase[J]. Clin Gastroenterol Hepatol, 2021, DOI: 10.1016/j.cgh.2021.01.019.[Online ahead of print]
    [4]
    SPRADLING PR, XING J, RUPP LB, et al. Distribution of disease phase, treatment prescription and severe liver disease among 1598 patients with chronic hepatitis B in the Chronic Hepatitis Cohort Study, 2006-2013[J]. Aliment Pharmacol Ther, 2016, 44 (10): 1080-1089. DOI: 10.1111/apt.13802.
    [5]
    YAO K, LIU J, WANG J, et al. Distribution and clinical characteristics of patients with chronic hepatitis B virus infection in the grey zone[J]. J Viral Hepat, 2021, 28 (7): 1025-1033. DOI: 10.1111/jvh.13511.
    [6]
    HSU YN, PAN CQ, ABBASI A, et al. Clinical presentation and disease phases of chronic hepatitis B using conventional versus modified ALT criteria in Asian Americans[J]. Dig Dis Sci, 2014, 59 (4): 865-871. DOI: 10.1007/s10620-014-3054-1.
    [7]
    DUAN M, CHI X, XIAO H, et al. High-normal alanine aminotransferase is an indicator for liver histopathology in HBeAg-negative chronic hepatitis B[J]. Hepatol Int, 2021, 15 (2): 318-327. DOI: 10.1007/s12072-021-10153-2.
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