Pathogenesis of coronavirus disease 2019 with liver injury

Lu LI; Shuang LI; Yu CHEN

doi:10.3969/j.issn.1001-5256.2021.01.046

Volume 37 Issue 1

Jan. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(1): 209-211

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Pathogenesis of coronavirus disease 2019 with liver injury

DOI: 10.3969/j.issn.1001-5256.2021.01.046

Lu LI^{1a, 2},
Shuang LI^{1b, 2},
Yu CHEN^{1a, 2
,}

1a.
Hepatology Center Department 4, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
1b.
Hemodialysis Room, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
2.
Beijing Municipal Key Laboratory of Liver Failure and Artificial Liver Treatment Research, Beijing 100069, China

Received Date: 2020-07-04
Accepted Date: 2020-07-30
Published Date: 2021-01-20

Abstract

Abstract

Coronavirus disease 2019 (COVID-19) has become a major threat to global public health. In addition to injury in the respiratory system, some patients may have varying degrees of liver injury. With reference to related articles, this article analyzes the etiological characteristics and pathogenesis of COVID-19 and discusses the possible causes of COVID-19 with liver injury, including the direct effect of virus, inflammatory cytokine storm, drug-induced liver injury, hypoxic liver injury, and immune dysfunction. It is suggested that reasonable drugs should be selected in clinical practice to protect the liver and reduce the incidence rate of liver injury.
- Coronavirus Disease 2019,
- Chemical and Drug Induced Liver Injury,
- Therapeutics

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References(31)

References

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Pathogenesis of coronavirus disease 2019 with liver injury

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