|
[1] National Workshop on Fatty Liver and Alcoholic Liver Disease,Chinese Society of Hepatology,Chinese Medical Association;Fatty Liver Expert Committee,Chinese Medical Doctor Association. Guidelines of prevention and treatment for nonalcoholic fatty liver disease:A 2018 update[J]. J Clin Hepatol,2018,34(5):947-957.(in Chinese)中华医学会肝病学分会脂肪肝和酒精性肝病学组，中国医师协会脂肪性肝病专家委员会．非酒精性脂肪性肝病防治指南(2018年更新版)[J]．临床肝胆病杂志，2018,34(5):947-957.
|
|
[2] YOUNOSSI Z,TACKE F,ARRESE M,et al. Global perspectives on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis[J]. Hepatology,2019,69(6):2672-2682.
|
|
[3] DUC D,VIGNE S,POT C. Oxysterols in autoimmunity[J]. Int J Mol Sci,2019,20(18):4522.
|
|
[4] MA Z,DENG C,HU W,et al. Liver X receptors and their agonists:Targeting for cholesterol homeostasis and cardiovascular diseases[J]. Curr Issues Mol Biol,2017,22:41-64.
|
|
[5] HIEBL V,LADURNER A,LATKOLIK S,et al. Natural products as modulators of the nuclear receptors and metabolic sensors LXR,FXR and RXR[J]. Biotechnol Adv,2018,36(6):1657-1698.
|
|
[6] MOHAMMAD MB,SAEIDEH ZK,SOHRAB H,et al. ABCA1 and metabolic syndrome; a review of the ABCA1 role in HDL-VLDL production,insulin-glucose homeostasis,in flammation and obesity[J]. Diabetes Metab Syndr,2019,13(2):1529-1534.
|
|
[7] HARRIS MT,HUSSAIN SS,INOUYE CM,et al. Reinterpretation of the localization of the ATP binding cassette transporter ABCG1 in insulin-secreting cells and insights regarding its trafficking and function[J]. PLo S One, 2018, 13(9):e0198383.
|
|
[8] ZEIN AA,KAUR R,HUSSEIN T,et al. ABCG5/G8:A structural view to pathophysiology of the hepatobiliary cholesterol secretion[J]. Biochem Soc Trans,2019,47(5):1259-1268.
|
|
[9] TOYODA Y,TAKADA T,YAMANASHI Y,et al. Pathophysiological importance of bile cholesterol reabsorption:Hepatic NPC1L1-exacerbated steatosis and decreasing VLDL-TG secretion in mice fed a high-fat diet[J]. Lipids Health Dis,2019,18(1):234.
|
|
[10] KOMATI R,SPADONI D,ZHENG S,et al. Ligands of therapeutic utility for the liver X receptors[J]. Molecules,2017,22(1):88.
|
|
[11] WANG B,TONTONOZ P. Liver X receptors in lipid signalling and membrane homeostasis[J]. Nat Rev Endocrinol,2018,14(8):452-463.
|
|
[12] ORAM JF,HEINECKE JW. ATP binding cassette transporter A1:A cell cholesterol exporter that protects against cardiovascular disease[J]. Physiol Rev,2005,85(4):1343-1372.
|
|
[13] BANNO A,WANG J,OKADA K,et al. Identification of a novel cholesterol-lowering dipeptide, phenylalanine-proline(FP),and its down-regulation of intestinal ABCA1 in hypercholesterolemic rats and Caco-2 cells[J]. Sci Rep,2019,9(1):19416.
|
|
[14] VINCENT V,THAKKAR H,AGGARWAL S,et al. ATP-binding cassette transporter A1(ABCA1)expression in adipose tissue and its modulation with insulin resistance in obesity[J].Diabetes Metab Syndr Obes,2019,12:275-284.
|
|
[15] MARANGHI M,TRUGLIO G,GALLO A,et al. A novel splicing mutation in the ABCA1 gene,causing Tangier disease and familial HDL deficiency in a large family[J]. Biochem Biophys Res Commun,2019,508(2):487-493.
|
|
[16] EBNER L,GLSER A,BRUER A,et al. Evaluation of two liver treatment strategies in a mouse model of niemann-pick-disease type C1[J]. Int J Mol Sci,2018,19(4):972.
|
|
[17] WANG X,COLLINS HL,RANALLETTA M,et al. Macrophage ABCA1 and ABCG1,but not SR-BI,promote macrophage reverse cholesterol transport in vivo[J]. J Clin Invest,2007,117(8):2216-2224.
|
|
[18] YU L,YORK J,von BERGMANN K,et al. Stimulation of cholesterol excretion by the liver X receptor agonist requires ATPbinding cassette transporters G5 and G8[J]. J Biol Chem,2003,278(18):15565-15570.
|
|
[19] TANG W,JIA L,MA Y,et al. Ezetimibe restores biliary cholesterol excretion in mice expressing Niemann-Pick C1-Like1 only in liver[J]. Biochim Biophys Acta,2011,1811(9):549-555.
|
|
[20] RAMN-VZQUEZ A,de LA ROSA JV,TABRAUE C,et al.Common and differential transcriptional actions of nuclear receptors liver X receptorsαandβin macrophages[J]. Mol Cell Biol,2019,39(5):e00376-18.
|
|
[21] BEI C,RUN-BIN S,GENG Y,et al. Berberine reverses LPSinduced repression of CYP7A1 through an anti-inflammatory effect[J]. Chin Herb Med,2019,11(3):292-298.
|
|
[22] WANG YY,DAHLE MK,AGREN J,et al. Activation of the liver X receptor protects against hepatic injury in endotoxemia by suppressing Kupffer cell activation[J]. Shock,2006,25(2):141-146.
|
|
[23] ARCHER A,LAURENCIKIENE J,AHMED O,et al. Skeletal muscle as a target of LXR agonist after long-term treatment:Focus on lipid homeostasis[J]. Am J Physiol Endocrinol Metab,2014,306(5):e494-e502.
|
|
[24] LIU Y,HAN X,BIAN Z,et al. Activation of liver X receptors attenuates endotoxin-induced liver injury in mice with nonalcoholic fatty liver disease[J]. Dig Dis Sci,2012,57(2):390-398.
|
|
[25] MUSSO G,GAMBINO R,CASSADER M. Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis[J]. Prog Lipid Res,2013,52(1):175-191.
|
|
[26] TALL AR,YVAN-CHARVET L. Cholesterol,inflammation and innate immunity[J]. Nat Rev Immunol,2015,15(2):104-116.
|
|
[27] NI M,ZHANG B,ZHAO J,et al. Biological mechanisms and related natural modulators of liver X receptor in nonalcoholic fatty liver disease[J]. Biomed Pharmacother,2019,113:108778.
|
|
[28] AYAKA I,CYNTHIA H,RONG X,et al. LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling[J]. Elife,2015,4:e08009.
|
|
[29] ANTOINE J,THIBAUT B,LOUISE M,et al. Revisiting the role of LXRs in PUFA metabolism and phospholipid homeostasis[J]. Int J Mol Sci,2019,20(15):3787-3797.
|
|
[30] GAO MM,LIU DX. The liver X receptor agonist T0901317 protects mice from high fat diet-induced obesity and insulin resistance[J]. AAPS J,2013,15(1):258-266.
|
|
[31] KNUT TD,STINE MU,KRISTER B,et al. Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptorα[J]. J Biol Chem,2003,278(48):48283-48291.
|
|
[32] BARANOWSKI M,ZABIELSKI P,BACHNIO-ZABIELSKA AU,et al. Insulin-sensitizing effect of LXR agonist T0901317 in high-fat fed rats is associated with restored muscle GLUT4 expression and insulin-stimulated AS160 phosphorylation[J]. Cell Physiol Biochem,2014,33(4):1047-1057.
|
|
[33] MARYC S,MARKJ H. Role of nuclear receptors in the modulation of insulin secretion in lipid-induced insulin resistance[J]. Biochem Soc Trans,2008,36(Pt 5):891-900.
|
|
[34] DONG Y,GAO GR,FAN HY,et al. Activation of the liver X receptor by agonist TO901317 improves hepatic insulin resistance via suppressing reactive oxygen species and JNK pathway[J]. PLo S One,2015,10(4):e0124778.
|
|
[35] PETTERSSON AML,STENSON BM,LORENTE CS,et al. LXR is a negative regulator of glucose uptake in human adipocytes[J]. Diabetologia,2013,56(9):2044-2054.
|
|
[36] KAORI EU,MAKOTO M,Liver X receptors regulate cholesterol metabolism and immunity in hepatic nonparenchymal cells[J]. Int J Mol Sci,2019,20(20):5045-5061.
|
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