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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 36 Issue 8
Aug.  2020
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Article Contents

Mechanism of the inhibitory effect of galangin on hepatoma cells

DOI: 10.3969/j.issn.1001-5256.2020.08.040
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  • Published Date: 2020-08-20
  • The mortality rate of hepatocellular carcinoma(HCC) remains high,and although there have been several treatment methods,HCC patients still have poor treatment outcome and prognosis in clinical practice.Therefore,it is necessary to find a new drug for the treatment of HCC to improve patients' survival rate.This article introduces a new antitumor drug,galangin,which can exert an antitumor effect by inhibiting cell proliferation,promoting apoptosis,inducing autophagy,and inhibiting metastasis.In addition,galangin can also inhibit angiogenesis in liver cancer,reverse multidrug resistance,and enhance the synergistic effect between drugs.Therefore,galangin is believed to have a promising future in clinical practice,and it is expected that more studies will focus on the anti-hepatoma cell mechanism of galangin to provide a scientific basis for the clinical translation of galangin.

     

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