Research advances in the risk factors for microvascular invasion in hepatocellular carcinoma

Liver cancer is one of the most common malignant tumors in the world,and at present,China has the highest incidence rate of liver cancer. Liver cancer has an insidious onset,and patients often have no obvious symptoms in the early stage; however,due to the rapid progression of this disease,most patients have developed advanced tumors at the time of diagnosis,and about 10% of patients have microvascular invasion( MVI) at initial pathological diagnosis. Although continuous improvement and progress have been made in the treatment methods for liver cancer,there is no significant reduction in postoperative recurrence rate. Many studies support that MVI is one of the independent risk factors for liver cancer recurrence,and patients with MVI determined by pathological diagnosis often have poor prognosis. However,there is still a lack of preoperative evaluation methods for MVI. This article analyzes and integrates the studies on MVI in the past 3 to5 years,in order to provide a comprehensive understanding of the research advances in MVI.