中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 3
Mar.  2019
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Article Contents

Role and mechanism of action of adipocytokines in the progression of liver fibrosis

DOI: 10.3969/j.issn.1001-5256.2019.03.043
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  • Received Date: 2018-09-21
  • Published Date: 2019-03-20
  • Liver fibrosis is an essential stage in the development and progression of liver cirrhosis, and uncontrolled liver fibrosis may even-tually lead to liver cirrhosis and/or hepatocellular carcinoma. Liver fibrosis is a dynamic process regulated by many factors. An increasingnumber of evidence has shown that adipokines transmit dynamic functions in the liver and are involved in the regulation of liver fibrosis. Thisarticle reviews the research on major adipocytokines ( adiponectin and leptin) involved in liver fibrosis and the recent advances in the mecha-nism of action of these adipocytokines in liver fibrosis.

     

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