中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 2
Feb.  2019
Turn off MathJax
Article Contents

Research advances in the epidemiological features, pathogenesis, and diagnosis and treatment of alcoholic pancreatitis

DOI: 10.3969/j.issn.1001-5256.2019.02.047
  • Received Date: 2018-09-05
  • Published Date: 2019-02-20
  • There has been a significant increase in the number of patients with alcoholic pancreatitis in recent years, and the pathogenesis of alcoholic pancreatitis is associated with various factors including genetic factors, smoking, and gut microbiota. Alcoholic pancreatitis is different from other types of pancreatitis in epidemiological features and clinical manifestations. This article reviews the research advances in the epidemiological features, pathogenesis, clinical manifestations, treatment, and prognosis of alcoholic pancreatitis.

     

  • loading
  • [1]ZHU Y, PAN X, ZENG H.A study on the etiology, severity, and mortality of 3260 patients with acute pancreatitis according to the revised Atlanta classification in Jiangxi, China over an 8-year period[J].Pancreas, 2017, 46 (4) :504-509.
    [2]WANG GJ, GAO CF, WEI D, et al.Acute pancreatitis:Etiology and common pathogenesis[J].World J Gastroenterol, 2009, 15 (12) :1427-1430.
    [3]LU ZY, ZHONG NS.Internal medicine[M].7th Edition.Beijing:People's Medical Publishing House, 2008:379-380. (in Chinese) 陆再英, 钟南山.内科学[M].7版.北京:人民卫生出版社, 2008:379-380.
    [4]WANG JY, LIAO EY, HUANG CX.Internal medicine (8-year medical program) [M].2th Edition.Beijing:People's Medical Publishing House, 2010:555-556. (in Chinese) 王吉耀, 廖二元, 黄从新.内科学 (八年制) [M].2版.北京:人民卫生出版社, 2010:555-556.
    [5]BHARDWAJ P, GARG PK, MAULIK SK.A randomized controlled trial of antioxidant supplementation for pain relief in patients with chronic pancreatitis[J].Gastroenterology, 2009, 136 (1) :149-159.e2.
    [6]KARJULA H, SAARELA A, OHTONEN P.Long-term outcome and causes of death for working-age patients hospitalized due to acute pancreatitis with a median follow-up of 10years[J].Ann Surg, 2017.[Epub ahead of print]
    [7]CONWELL DL, BANKS PA, SANDHU BS.Validation of demographics, etiology, and risk factors for chronic pancreatitis in the USA:A report of the North American Pancreas Study (NAPS) Group[J].Dig Dis Sci, 2017, 62 (8) :2133-2140.
    [8]ZHENG Y, ZHOU Z, LI H.A multicenter study on etiology of acute pancreatitis in Beijing during 5 years[J].Pancreas, 2015, 44 (3) :409-414.
    [9]KUME K, MASAMUNE A, ARIGA H, et al.Alcohol consumption and the risk for developing pancreatitis:A case-control study in Japan[J].Pancreas, 2015, 44 (1) :53-58.
    [10]SAMOKHVALOV AV, REHM J, ROERECKE M.Alcohol consumption as a risk factor for acute and chronic pancreatitis:Asystematic review and a series of Meta-analyses[J].EBioMedicine, 2015, 2 (12) :1996-2002.
    [11]LANKISCH PG, APTE M, BANKS PA, et al.Acute pancreatitis[J].Lancet, 2015, 386 (9988) :85-96.
    [12]CLEMENS DL, SCHNEIDER KJ, ARKFELD CK.Alcoholic pancreatitis:New insights into the pathogenesis and treatment[J].World J Gastrointest Pathophysiol, 2016, 7 (1) :48-58.
    [13]WHITCOMB DC, LARUSCH J, KRASINSKAS AM.Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis[J].Nat Genet, 2012, 44 (12) :1349-1354.
    [14]DERIKX MH, KOVACS P, SCHOLZ M.Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study[J].Gut, 2015, 64 (9) :1426-1433.
    [15]ROSENDAHL J, KIRSTEN H, HEGYI E.Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis[J].Gut, 2017, 67 (10) :1855-1863.
    [16]MAISONNEUVE P, LOWENFELS AB, MULLHAUPT B.Cigarette smoking accelerates progression of alcoholic chronic pancreatitis[J].Gut, 2005, 54 (4) :510-514.
    [17]LUGEA A, GERLOFF A, SU HY.The Combination of alcohol and cigarette smoke induces endoplasmic reticulum stress and cell death in pancreatic acinar cells[J].Gastroenterology, 2017, 153 (6) :1674-1686.
    [18]CIOCAN D, REBOURS V, VOICAN CS.Characterization of intestinal microbiota in alcoholic patients with and without alcoholic hepatitis or chronic alcoholic pancreatitis[J].Sci Rep, 2018, 8 (1) :4822.
    [19]CUI ML, KIM KH, KIM HG.Incidence, risk factors and clinical course of pancreatic fluid collections in acute pancreatitis[J].Dig Dis Sci, 2014, 59 (5) :1055-1062.
    [20]HOLLEMANS RA, HALLENSLEBEN NDL, MAGER DJ.Pancreatic exocrine insufficiency following acute pancreatitis:Systematic review and study level meta-analysis[J].Pancreatology, 2018, 18 (3) :253-262.
    [21]YANG L, XU J, LAI XR, et al.Effect of nutritional support on the prognosis of patients with acute pancreatitis[J].Chin JMed Offic, 2018, 46 (7) :790-793. (in Chinese) 杨蕾, 徐静, 赖晓蕊, 等.不同营养支持方式对急性胰腺炎预后影响[J].临床军医杂志, 2018, 46 (7) :790-793.
    [22]NIKKOLA J, RATY S, LAUKKARINEN J, et al.Abstinence after first acute alcohol-associated pancreatitis protects against recurrent pancreatitis and minimizes the risk of pancreatic dysfunction[J].Alcohol Alcohol, 2013, 48 (4) :483-486.
    [23]SHI XM, WEI SC.Analysis of clinical efficacy of compound azintamide enteric-coated tablets in the treatment of chronic alcoholic pancreatitis indigestion[J].Syst Med, 2017, 20 (2) :48-50, 53. (in Chinese) 史晓盟, 魏思忱.泌特治疗慢性酒精性胰腺炎消化不良临床疗效分析[J].系统医学, 2017, 20 (2) :48-50, 53.
    [24]AHMED ALI U, ISSA Y, HAGENAARS JC.Risk of recurrent pancreatitis and progression to chronic pancreatitis after a first episode of acute pancreatitis[J].Clin Gastroenterol Hepatol, 2016, 14 (5) :738-746.
    [25]CHO JH, KIM TN, KIM SB.Comparison of clinical course and outcome of acute pancreatitis according to the two main etiologies:Alcohol and gallstone[J].BMC Gastroenterol, 2015, 15 (1) :87.
    [26]HAO L, WANG LS, LIU Y.The different course of alcoholic and idiopathic chronic pancreatitis:A long-term study of2037 patients[J].PLo S One, 2018, 13 (6) :e0198365.
    [27]CROCKETT SD, WANI S, GARDNER TB.American Gastroenterological Association Institute Guideline on initial management of acute pancreatitis[J].Gastroenterology, 2018, 154 (4) :1096-1101.
    [28]GBD 2016 Alcohol Collaborators.Alcohol use and burden for195 countries and territories, 1990-2016:A systematic analysis for the Global Burden of Disease Study 2016[J].The Lancet, 2018, 392 (10152) :1015-1035.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1464) PDF downloads(374) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return