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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 1
Jan.  2019
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Article Contents

Advances in the diagnosis and treatment of non-cirrhotic sinusoidal portal hypertension

DOI: 10.3969/j.issn.1001-5256.2019.01.003
  • Published Date: 2019-01-20
  • The common causes of non-cirrhotic sinusoidal hypertension were intrahepatic diseases that involves sinusoidal or perisinusoidal space, with sinusoidal obstruction syndrome being a common etiology, which was mainly caused by chemotherapy or radiotherapy prior to hematopoietic stem cell transplantation and pyrrolizidine alkaloid herbal therapy;defibrotide was the only approved drug for this disease. The other causes included nodular regenerative hyperplasia, which were mainly diagnosed by liver pathophysiology;treatment remains largely tar geted at the individual sequalae of portal hypertension and respective potential causes.

     

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