Value of endoscopic ultrasonography in diagnosis of pancreatic space-occupying diseases

Objective To investigate the value of endoscopic ultrasonography ( EUS) in the diagnosis of pancreatic space-occupying diseases. Methods A total of 85 patients with suspected pancreatic space-occupying diseases who were treated in The Second Affiliated Hospital of Jiaxing College from January 2015 to January 2017 were enrolled. Surgical pathological results or follow-up results were used as the gold standard for evaluating the value of EUS and EUS-guided fine needle aspiration ( EUS-FNA) in the diagnosis of pancreatic space-occupying diseases. The chi-square test was used for comparison of categorical data between groups. Results EUS had an imaging detection rate of 96. 7% ( 59/61) , a specificity of 100% ( 24/24) , and an accuracy rate of 97. 6% ( 83/85) in the diagnosis of pancreatic space-occupying diseases; EUS had significantly higher detection rate and accuracy rate than abdominal ultrasound, computed tomography, and magnetic resonance imaging ( detection rate: χ2= 4. 344, 3. 873, and 15. 445, all P < 0. 05; accuracy rate: χ2= 6. 675, 8. 685, and 17. 389, all P <0. 05) . EUS-FNA had a detection rate of 81. 8% ( 45/55) and an accuracy rate of 81. 0% ( 47/58) . Among the patients who underwent surgery to have pathological results, the overall coincidence rate of preoperative EUS-FNA was 84. 2% ( 16/19) . Conclusion Compared with conventional imaging examinations, EUS has a higher diagnostic accuracy for pancreatic space-occupying diseases, and EUS-FNA can further clarify the nature and pathological type of space-occupying lesions. EUS may help with the early diagnosis and treatment of pancreatic tumors.